trichostatin A-5209 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-5209 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ARMCX2 armadillo repeat containing, X-linked 2
BEX4 brain expressed, X-linked 4
BMP7 bone morphogenetic protein 7
CCNG2 cyclin G2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIXDC1 DIX domain containing 1
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EGR1 early growth response 1
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
ETV5 ets variant 5
FAM105A family with sequence similarity 105, member A
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GRAMD1C GRAM domain containing 1C
GRK5 G protein-coupled receptor kinase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAG1 jagged 1
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MVP major vault protein
MXRA7 matrix-remodelling associated 7
NES nestin
NME5 NME/NM23 family member 5
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLLP plasmolipin
PRPH peripherin
PTRF polymerase I and transcript release factor
RAB29 RAB29, member RAS oncogene family
RAI2 retinoic acid induced 2
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TBXA2R thromboxane A2 receptor
TNIK TRAF2 and NCK interacting kinase
TRAFD1 TRAF-type zinc finger domain containing 1
TTC33 tetratricopeptide repeat domain 33
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AEN apoptosis enhancing nuclease
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHKB choline kinase beta
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DCTN4 dynactin 4 (p62)
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ESRP2 epithelial splicing regulatory protein 2
FAM155B family with sequence similarity 155, member B
FAM57A family with sequence similarity 57, member A
FERMT1 fermitin family member 1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GLMN glomulin, FKBP associated protein
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
HEATR3 HEAT repeat containing 3
HMGB3 high mobility group box 3
INHBB inhibin, beta B
IRX5 iroquois homeobox 5
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LMNB1 lamin B1
LPAR2 lysophosphatidic acid receptor 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTD1 mbt domain containing 1
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL8 methyltransferase like 8
MPDU1 mannose-P-dolichol utilization defect 1
MPPED2 metallophosphoesterase domain containing 2
MSL1 male-specific lethal 1 homolog (Drosophila)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NHEJ1 nonhomologous end-joining factor 1
NMI N-myc (and STAT) interactor
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHA6 protocadherin alpha 6
PCNT pericentrin
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POGK pogo transposable element with KRAB domain
PPCS phosphopantothenoylcysteine synthetase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD8 SET domain containing (lysine methyltransferase) 8
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TCTN2 tectonic family member 2
THOC6 THO complex 6
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
UBXN8 UBX domain protein 8
USP16 ubiquitin specific peptidase 16
USP21 ubiquitin specific peptidase 21
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692