trichostatin A-4821 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the trichostatin A-4821 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
ANGPTL4 angiopoietin-like 4
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP3 BAI1-associated protein 3
C19ORF66 chromosome 19 open reading frame 66
CA5B carbonic anhydrase VB, mitochondrial
CCDC88A coiled-coil domain containing 88A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
FAM13A family with sequence similarity 13, member A
FAM46C family with sequence similarity 46, member C
FAM49A family with sequence similarity 49, member A
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HYAL1 hyaluronoglucosaminidase 1
IFI6 interferon, alpha-inducible protein 6
IL21R interleukin 21 receptor
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF13B kinesin family member 13B
KIF21B kinesin family member 21B
LINC00341 long intergenic non-protein coding RNA 341
LYST lysosomal trafficking regulator
MAST3 microtubule associated serine/threonine kinase 3
MLXIPL MLX interacting protein-like
MMD monocyte to macrophage differentiation-associated
NAP1L3 nucleosome assembly protein 1-like 3
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NES nestin
NME5 NME/NM23 family member 5
NXN nucleoredoxin
PAIP2B poly(A) binding protein interacting protein 2B
PCLO piccolo presynaptic cytomatrix protein
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PMEL premelanosome protein
PRPH peripherin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNFT1 ring finger protein, transmembrane 1
RPL3L ribosomal protein L3-like
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TMSB15A thymosin beta 15a
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
USP2 ubiquitin specific peptidase 2
WDR47 WD repeat domain 47
ZCCHC14 zinc finger, CCHC domain containing 14
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATAD2B ATPase family, AAA domain containing 2B
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C17ORF75 chromosome 17 open reading frame 75
C7ORF49 chromosome 7 open reading frame 49
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CCNL2 cyclin L2
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EFNA1 ephrin-A1
EGR3 early growth response 3
FAM57A family with sequence similarity 57, member A
FAM60A family with sequence similarity 60, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GMEB1 glucocorticoid modulatory element binding protein 1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOXC11 homeobox C11
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
KIF15 kinesin family member 15
LMNB1 lamin B1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MED15 mediator complex subunit 15
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPDU1 mannose-P-dolichol utilization defect 1
MPPED2 metallophosphoesterase domain containing 2
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PUS1 pseudouridylate synthase 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCRN1 secernin 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SIDT1 SID1 transmembrane family, member 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC35F2 solute carrier family 35, member F2
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SPAG7 sperm associated antigen 7
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
SYTL2 synaptotagmin-like 2
TMEM62 transmembrane protein 62
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
URGCP upregulator of cell proliferation
XBP1 X-box binding protein 1
XPO7 exportin 7
YAP1 Yes-associated protein 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF280D zinc finger protein 280D
ZNF33B zinc finger protein 33B
ZNF668 zinc finger protein 668
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2