trichostatin A-4665 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-4665 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BMP4 bone morphogenetic protein 4
C18ORF8 chromosome 18 open reading frame 8
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CLTCL1 clathrin, heavy chain-like 1
COL9A3 collagen, type IX, alpha 3
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
DENND3 DENN/MADD domain containing 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB3 EPH receptor B3
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GJA8 gap junction protein, alpha 8, 50kDa
HIRA histone cell cycle regulator
HOXA1 homeobox A1
IL11 interleukin 11
IRF6 interferon regulatory factor 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
KITLG KIT ligand
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPIN1 lipin 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LYPD3 LY6/PLAUR domain containing 3
LYST lysosomal trafficking regulator
MAK male germ cell-associated kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MCTP2 multiple C2 domains, transmembrane 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NGF nerve growth factor (beta polypeptide)
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDH9 protocadherin 9
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER1 period circadian clock 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLXNA3 plexin A3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNF24 ring finger protein 24
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STON1 stonin 1
STX7 syntaxin 7
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
THEMIS2 thymocyte selection associated family member 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIK TRAF2 and NCK interacting kinase
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
USP2 ubiquitin specific peptidase 2
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VGLL3 vestigial-like family member 3

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARSJ arylsulfatase family, member J
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF1 activating transcription factor 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BNC2 basonuclin 2
C19ORF40 chromosome 19 open reading frame 40
CBR3 carbonyl reductase 3
CCDC59 coiled-coil domain containing 59
CCDC94 coiled-coil domain containing 94
CDC7 cell division cycle 7
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FADD Fas (TNFRSF6)-associated via death domain
FAM120C family with sequence similarity 120C
FAM169A family with sequence similarity 169, member A
FAM178A family with sequence similarity 178, member A
FAM60A family with sequence similarity 60, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIF1 ligand dependent nuclear receptor interacting factor 1
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL4 methyltransferase like 4
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MTPAP mitochondrial poly(A) polymerase
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NHLRC2 NHL repeat containing 2
NLRX1 NLR family member X1
NMI N-myc (and STAT) interactor
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PALMD palmdelphin
PARP12 poly (ADP-ribose) polymerase family, member 12
PEG3 paternally expressed 3
PEX14 peroxisomal biogenesis factor 14
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
RIN2 Ras and Rab interactor 2
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPOP speckle-type POZ protein
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGIF1 TGFB-induced factor homeobox 1
TUBGCP3 tubulin, gamma complex associated protein 3
URGCP upregulator of cell proliferation
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
ZNF165 zinc finger protein 165
ZNF32 zinc finger protein 32
ZNF606 zinc finger protein 606
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76
ZNF787 zinc finger protein 787
ZZZ3 zinc finger, ZZ-type containing 3