trichostatin A-4483 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-4483 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP26 Rho GTPase activating protein 26
ASMTL acetylserotonin O-methyltransferase-like
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BIRC3 baculoviral IAP repeat containing 3
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BTF3P11 basic transcription factor 3 pseudogene 11
C2CD2L C2CD2-like
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CLTCL1 clathrin, heavy chain-like 1
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DFNB31 deafness, autosomal recessive 31
DIAPH2-AS1 DIAPH2 antisense RNA 1
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EGR2 early growth response 2
ELOVL4 ELOVL fatty acid elongase 4
EPHB3 EPH receptor B3
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FLJ21369 uncharacterized protein FLJ21369
GPC3 glypican 3
H1FX H1 histone family, member X
IGHA1 immunoglobulin heavy constant alpha 1
IGSF3 immunoglobulin superfamily, member 3
IL1RAP interleukin 1 receptor accessory protein
INSIG1 insulin induced gene 1
ITGA7 integrin, alpha 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0930 KIAA0930
KIF5C kinesin family member 5C
LIFR leukemia inhibitory factor receptor alpha
LMCD1 LIM and cysteine-rich domains 1
MAP2 microtubule-associated protein 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MERTK MER proto-oncogene, tyrosine kinase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAG18 NAG18 mRNA
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU1 sialidase 1 (lysosomal sialidase)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRXN3 neurexin 3
OASL 2'-5'-oligoadenylate synthetase-like
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PELI2 pellino E3 ubiquitin protein ligase family member 2
PLK2 polo-like kinase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTK2B protein tyrosine kinase 2 beta
PTPRH protein tyrosine phosphatase, receptor type, H
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAI2 retinoic acid induced 2
RARA retinoic acid receptor, alpha
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RNF19B ring finger protein 19B
RNF24 ring finger protein 24
RUNX1 runt-related transcription factor 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIX3 SIX homeobox 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SP100 SP100 nuclear antigen
SPATA1 spermatogenesis associated 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF1 sterol regulatory element binding transcription factor 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TJP3 tight junction protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM3 tripartite motif containing 3
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZFP36 ZFP36 ring finger protein
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ARSJ arylsulfatase family, member J
ATF1 activating transcription factor 1
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
C9ORF91 chromosome 9 open reading frame 91
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CHM choroideremia (Rab escort protein 1)
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTPS1 CTP synthase 1
CUL1 cullin 1
DEPDC1 DEP domain containing 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DSC2 desmocollin 2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FST follistatin
GABPB1 GA binding protein transcription factor, beta subunit 1
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2I general transcription factor IIi
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
IL7R interleukin 7 receptor
IRS1 insulin receptor substrate 1
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MCMBP minichromosome maintenance complex binding protein
MEPCE methylphosphate capping enzyme
METTL4 methyltransferase like 4
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MX1 MX dynamin-like GTPase 1
NCS1 neuronal calcium sensor 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NOD1 nucleotide-binding oligomerization domain containing 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PALMD palmdelphin
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPAN peter pan homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRMT2 protein arginine methyltransferase 2
PTK6 protein tyrosine kinase 6
RBM22 RNA binding motif protein 22
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN2 Ras and Rab interactor 2
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD1B SET domain containing 1B
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STAG1 stromal antigen 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TCEAL1 transcription elongation factor A (SII)-like 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMED1 transmembrane emp24 protein transport domain containing 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TSSC4 tumor suppressing subtransferable candidate 4
TUBGCP3 tubulin, gamma complex associated protein 3
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF165 zinc finger protein 165
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN31 zinc finger and SCAN domain containing 31