trichostatin A-4388 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-4388 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL4 angiopoietin-like 4
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP3 BAI1-associated protein 3
CA5B carbonic anhydrase VB, mitochondrial
CASC1 cancer susceptibility candidate 1
CCNA1 cyclin A1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
FAM105A family with sequence similarity 105, member A
FAM49A family with sequence similarity 49, member A
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
HYAL1 hyaluronoglucosaminidase 1
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
MAOA monoamine oxidase A
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLXIPL MLX interacting protein-like
MUC3B mucin 3B, cell surface associated
NAP1L3 nucleosome assembly protein 1-like 3
NES nestin
NIPAL3 NIPA-like domain containing 3
NRTN neurturin
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLLP plasmolipin
PRPH peripherin
RAI2 retinoic acid induced 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RPL3L ribosomal protein L3-like
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
THEMIS2 thymocyte selection associated family member 2
TIMP3 TIMP metallopeptidase inhibitor 3
TUFT1 tuftelin 1
ULBP2 UL16 binding protein 2
VWA5A von Willebrand factor A domain containing 5A
XYLT1 xylosyltransferase I
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AEN apoptosis enhancing nuclease
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
BATF basic leucine zipper transcription factor, ATF-like
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C5AR2 complement component 5a receptor 2
CALHM2 calcium homeostasis modulator 2
CAPN15 calpain 15
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CCNO cyclin O
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTCF CCCTC-binding factor (zinc finger protein)
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM57A family with sequence similarity 57, member A
FAS Fas cell surface death receptor
FJX1 four jointed box 1 (Drosophila)
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
HIST1H1D histone cluster 1, H1d
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC41 leucine rich repeat containing 41
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL16 methyltransferase like 16
METTL8 methyltransferase like 8
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHB3 protocadherin beta 3
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STAG1 stromal antigen 1
STBD1 starch binding domain 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TMEM30B transmembrane protein 30B
TMPO thymopoietin
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBXN8 UBX domain protein 8
UCK2 uridine-cytidine kinase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787