trichostatin A-4348 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-4348 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ASPH aspartate beta-hydroxylase
ATP9B ATPase, class II, type 9B
BCO1 beta-carotene oxygenase 1
BST2 bone marrow stromal cell antigen 2
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCR calcitonin receptor
CAV3 caveolin 3
CC2D1A coiled-coil and C2 domain containing 1A
CCL5 chemokine (C-C motif) ligand 5
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CES3 carboxylesterase 3
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDN17 claudin 17
COLGALT2 collagen beta(1-O)galactosyltransferase 2
DNALI1 dynein, axonemal, light intermediate chain 1
DOCK6 dedicator of cytokinesis 6
ECM1 extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELN elastin
ELOVL5 ELOVL fatty acid elongase 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FBN2 fibrillin 2
FGF14 fibroblast growth factor 14
FLJ22184
FRMD8 FERM domain containing 8
FXYD5 FXYD domain containing ion transport regulator 5
GAS2L1 growth arrest-specific 2 like 1
GDF5 growth differentiation factor 5
GFER growth factor, augmenter of liver regeneration
GK2 glycerol kinase 2
GRM3 glutamate receptor, metabotropic 3
HIST1H1B histone cluster 1, H1b
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICOS inducible T-cell co-stimulator
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL11 interleukin 11
INHBE inhibin, beta E
IVL involucrin
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT15 keratin 15, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LRRC61 leucine rich repeat containing 61
MAN2A2 mannosidase, alpha, class 2A, member 2
MIIP migration and invasion inhibitory protein
MORN1 MORN repeat containing 1
MPPE1 metallophosphoesterase 1
MUC2 mucin 2, oligomeric mucus/gel-forming
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDRG2 NDRG family member 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPHP1 nephronophthisis 1 (juvenile)
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR2F2 olfactory receptor, family 2, subfamily F, member 2
PALM paralemmin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGR polymeric immunoglobulin receptor
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PKP1 plakophilin 1
PLTP phospholipid transfer protein
PPARD peroxisome proliferator-activated receptor delta
PTHLH parathyroid hormone-like hormone
RAB6B RAB6B, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHO rhodopsin
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS11 ribosomal protein S11
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SGK2 serum/glucocorticoid regulated kinase 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SPINK4 serine peptidase inhibitor, Kazal type 4
STS steroid sulfatase (microsomal), isozyme S
SV2C synaptic vesicle glycoprotein 2C
TBRG4 transforming growth factor beta regulator 4
TBX3 T-box 3
TFR2 transferrin receptor 2
TMEM176A transmembrane protein 176A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS1 tensin 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM15 tripartite motif containing 15
TRIM36 tripartite motif containing 36
TTLL4 tubulin tyrosine ligase-like family member 4
WNT16 wingless-type MMTV integration site family, member 16
ZC3H13 zinc finger CCCH-type containing 13
ZEB1 zinc finger E-box binding homeobox 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACAD10 acyl-CoA dehydrogenase family, member 10
ARMC4 armadillo repeat containing 4
ARPIN actin-related protein 2/3 complex inhibitor
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C10ORF88 chromosome 10 open reading frame 88
C11ORF30 chromosome 11 open reading frame 30
CASC1 cancer susceptibility candidate 1
CBX2 chromobox homolog 2
CCDC69 coiled-coil domain containing 69
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DCAF13 DDB1 and CUL4 associated factor 13
DCAF16 DDB1 and CUL4 associated factor 16
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNASE1L2 deoxyribonuclease I-like 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVPL envoplakin
FAM46C family with sequence similarity 46, member C
FBXL8 F-box and leucine-rich repeat protein 8
FSHB follicle stimulating hormone, beta polypeptide
GAS2 growth arrest-specific 2
GATA4 GATA binding protein 4
GMEB1 glucocorticoid modulatory element binding protein 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTP1 glutathione S-transferase pi 1
GUSBP3 glucuronidase, beta pseudogene 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIRA histone cell cycle regulator
HIST1H2AK histone cluster 1, H2ak
HPS6 Hermansky-Pudlak syndrome 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT83 keratin 83, type II
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LRRC37A3 leucine rich repeat containing 37, member A3
MDM4 MDM4, p53 regulator
NIPAL2 NIPA-like domain containing 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI3 peptidyl arginine deiminase, type III
PICK1 protein interacting with PRKCA 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMCH pro-melanin-concentrating hormone
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
R3HCC1L R3H domain and coiled-coil containing 1-like
RCAN3 RCAN family member 3
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
S100A7 S100 calcium binding protein A7
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SETD1B SET domain containing 1B
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNIP1 Smad nuclear interacting protein 1
SNTA1 syntrophin, alpha 1
STON1 stonin 1
SYCP2 synaptonemal complex protein 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TEX14 testis expressed 14
TM4SF5 transmembrane 4 L six family member 5
TMEM19 transmembrane protein 19
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOR4A torsin family 4, member A
TSGA10 testis specific, 10
TTBK2 tau tubulin kinase 2
TTC33 tetratricopeptide repeat domain 33
USP27X ubiquitin specific peptidase 27, X-linked
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF204P zinc finger protein 204, pseudogene
ZNF205 zinc finger protein 205
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF551 zinc finger protein 551