trichostatin A-4237 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-4237 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AGTR1 angiotensin II receptor, type 1
AHNAK2 AHNAK nucleoprotein 2
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CA5B carbonic anhydrase VB, mitochondrial
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CNTNAP2 contactin associated protein-like 2
COL21A1 collagen, type XXI, alpha 1
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA3 EPH receptor A3
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GMPR guanosine monophosphate reductase
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAP1 huntingtin-associated protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXA1 homeobox A1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
ITGA7 integrin, alpha 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KLF4 Kruppel-like factor 4 (gut)
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP2 microtubule-associated protein 2
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NME5 NME/NM23 family member 5
NOL4 nucleolar protein 4
PCDH17 protocadherin 17
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PML promyelocytic leukemia
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RNF24 ring finger protein 24
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STON1 stonin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAGLN3 transgelin 3
TMSB15A thymosin beta 15a
TNIK TRAF2 and NCK interacting kinase
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM36 tripartite motif containing 36
TRIM9 tripartite motif containing 9
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANP32A-IT1 ANP32A intronic transcript 1
ARSJ arylsulfatase family, member J
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C19ORF40 chromosome 19 open reading frame 40
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCNJ cyclin J
CDC7 cell division cycle 7
CLCF1 cardiotrophin-like cytokine factor 1
CLIP1 CAP-GLY domain containing linker protein 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTCF CCCTC-binding factor (zinc finger protein)
DEPDC1 DEP domain containing 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FADD Fas (TNFRSF6)-associated via death domain
FAIM Fas apoptotic inhibitory molecule
FAM120C family with sequence similarity 120C
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBX2 gastrulation brain homeobox 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL24 interleukin 24
INHBB inhibin, beta B
ITPKB inositol-trisphosphate 3-kinase B
KAT6B K(lysine) acetyltransferase 6B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
KIRREL kin of IRRE like (Drosophila)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
NPFFR1 neuropeptide FF receptor 1
NRIP1 nuclear receptor interacting protein 1
OSMR oncostatin M receptor
PARP4 poly (ADP-ribose) polymerase family, member 4
PCNT pericentrin
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLK1 polo-like kinase 1
PPAP2B phosphatidic acid phosphatase type 2B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKX protein kinase, X-linked
PTK6 protein tyrosine kinase 6
QRICH1 glutamine-rich 1
RBM23 RNA binding motif protein 23
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SOX12 SRY (sex determining region Y)-box 12
SPHK1 sphingosine kinase 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRIB3 tribbles pseudokinase 3
TSKU tsukushi, small leucine rich proteoglycan
UBXN8 UBX domain protein 8
VEGFC vascular endothelial growth factor C
WDR33 WD repeat domain 33
WDR74 WD repeat domain 74
ZBED1 zinc finger, BED-type containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZNF165 zinc finger protein 165
ZNF282 zinc finger protein 282
ZNF76 zinc finger protein 76
ZSCAN31 zinc finger and SCAN domain containing 31