trichostatin A-4184 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-4184 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BBC3 BCL2 binding component 3
BCL6 B-cell CLL/lymphoma 6
CA5B carbonic anhydrase VB, mitochondrial
CDC14B cell division cycle 14B
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
COBL cordon-bleu WH2 repeat protein
COL21A1 collagen, type XXI, alpha 1
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOPEY1 dopey family member 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
ELOVL4 ELOVL fatty acid elongase 4
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB3 EPH receptor B3
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXA1 homeobox A1
IRF6 interferon regulatory factor 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF5C kinesin family member 5C
LIFR leukemia inhibitory factor receptor alpha
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
NBEA neurobeachin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOL4 nucleolar protein 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OSR2 odd-skipped related transciption factor 2
PCDH17 protocadherin 17
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI2 pellino E3 ubiquitin protein ligase family member 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SHROOM2 shroom family member 2
SIRT4 sirtuin 4
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STOM stomatin
STON1 stonin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TESK2 testis-specific kinase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIK TRAF2 and NCK interacting kinase
TRIM36 tripartite motif containing 36
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOL6 apolipoprotein L, 6
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSJ arylsulfatase family, member J
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C19ORF40 chromosome 19 open reading frame 40
C7ORF49 chromosome 7 open reading frame 49
C9ORF40 chromosome 9 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CBX8 chromobox homolog 8
CCNT1 cyclin T1
CDT1 chromatin licensing and DNA replication factor 1
CLCF1 cardiotrophin-like cytokine factor 1
COG7 component of oligomeric golgi complex 7
COIL coilin
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DEPDC1 DEP domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FADD Fas (TNFRSF6)-associated via death domain
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD8 frizzled class receptor 8
GBX2 gastrulation brain homeobox 2
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAT6B K(lysine) acetyltransferase 6B
KDM4D lysine (K)-specific demethylase 4D
KEAP1 kelch-like ECH-associated protein 1
KIRREL kin of IRRE like (Drosophila)
LIF leukemia inhibitory factor
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC41 leucine rich repeat containing 41
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MEPCE methylphosphate capping enzyme
MFSD5 major facilitator superfamily domain containing 5
MRPS2 mitochondrial ribosomal protein S2
MSL1 male-specific lethal 1 homolog (Drosophila)
NINJ1 ninjurin 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARP4 poly (ADP-ribose) polymerase family, member 4
PMM2 phosphomannomutase 2
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRB3 proline-rich protein BstNI subfamily 3
PRCC papillary renal cell carcinoma (translocation-associated)
PXDC1 PX domain containing 1
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SH2D4A SH2 domain containing 4A
SIM2 single-minded family bHLH transcription factor 2
SLC12A8 solute carrier family 12, member 8
SLITRK5 SLIT and NTRK-like family, member 5
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMYD5 SMYD family member 5
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARBP2 TAR (HIV-1) RNA binding protein 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLN1 talin 1
TMEM39B transmembrane protein 39B
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRPM2 transient receptor potential cation channel, subfamily M, member 2
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WNT7A wingless-type MMTV integration site family, member 7A
XAB2 XPA binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNF804A zinc finger protein 804A
ZSCAN31 zinc finger and SCAN domain containing 31