trichostatin A-413 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-413 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRE5 adhesion G protein-coupled receptor E5
AGTR2 angiotensin II receptor, type 2
AHNAK2 AHNAK nucleoprotein 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATXN8OS ATXN8 opposite strand (non-protein coding)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTN2A1 butyrophilin, subfamily 2, member A1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CDH22 cadherin 22, type 2
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNGB3 cyclic nucleotide gated channel beta 3
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIXDC1 DIX domain containing 1
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DOPEY1 dopey family member 1
DTNB dystrobrevin, beta
EPOR erythropoietin receptor
FBXL2 F-box and leucine-rich repeat protein 2
FGD6 FYVE, RhoGEF and PH domain containing 6
FN1 fibronectin 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLRX glutaredoxin (thioltransferase)
GM2A GM2 ganglioside activator
GP2 glycoprotein 2 (zymogen granule membrane)
GSK3A glycogen synthase kinase 3 alpha
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HEMK1 HemK methyltransferase family member 1
HIST1H2AI histone cluster 1, H2ai
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING1 inhibitor of growth family, member 1
KIF5C kinesin family member 5C
KIFAP3 kinesin-associated protein 3
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LRRC14 leucine rich repeat containing 14
MAP1B microtubule-associated protein 1B
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MTL5 metallothionein-like 5, testis-specific (tesmin)
MVK mevalonate kinase
MYO9B myosin IXB
NADK NAD kinase
OPTN optineurin
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAB29 RAB29, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC46A3 solute carrier family 46, member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPTBN5 spectrin, beta, non-erythrocytic 5
STAB2 stabilin 2
STAC SH3 and cysteine rich domain
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX5 T-box 5
TMEM242 transmembrane protein 242
TMEM70 transmembrane protein 70
TMF1 TATA element modulatory factor 1
TNIK TRAF2 and NCK interacting kinase
TP63 tumor protein p63
TPMT thiopurine S-methyltransferase
TRAK1 trafficking protein, kinesin binding 1
TRIM2 tripartite motif containing 2
TUBB2A tubulin, beta 2A class IIa
UBOX5 U-box domain containing 5
ULBP2 UL16 binding protein 2
VARS valyl-tRNA synthetase
VPRBP Vpr (HIV-1) binding protein
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP8 aquaporin 8
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC4 armadillo repeat containing 4
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP9A ATPase, class II, type 9A
AXIN1 axin 1
BAGE B melanoma antigen
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C16ORF62 chromosome 16 open reading frame 62
C1QTNF1 C1q and tumor necrosis factor related protein 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNL2 cyclin L2
CD38 CD38 molecule
CD5 CD5 molecule
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CROT carnitine O-octanoyltransferase
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DAGLA diacylglycerol lipase, alpha
DBF4 DBF4 zinc finger
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYSF dysferlin
EPN3 epsin 3
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FJX1 four jointed box 1 (Drosophila)
FKBPL FK506 binding protein like
FOXC1 forkhead box C1
GAB2 GRB2-associated binding protein 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GTF2I general transcription factor IIi
GTPBP2 GTP binding protein 2
H2AFY2 H2A histone family, member Y2
HMGB3P1 high mobility group box 3 pseudogene 1
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
INHBB inhibin, beta B
IRX5 iroquois homeobox 5
KEAP1 kelch-like ECH-associated protein 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2L2 nuclear factor, erythroid 2-like 2
NMI N-myc (and STAT) interactor
NMU neuromedin U
NSD1 nuclear receptor binding SET domain protein 1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PEX12 peroxisomal biogenesis factor 12
PFAS phosphoribosylformylglycinamidine synthase
PHF11 PHD finger protein 11
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PISD phosphatidylserine decarboxylase
POGK pogo transposable element with KRAB domain
POMT2 protein-O-mannosyltransferase 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRMT3 protein arginine methyltransferase 3
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTBP2 polypyrimidine tract binding protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RFTN1 raftlin, lipid raft linker 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF208 ring finger protein 208
RNF220 ring finger protein 220
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC10A3 solute carrier family 10, member 3
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SUSD4 sushi domain containing 4
SYT13 synaptotagmin XIII
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGIF1 TGFB-induced factor homeobox 1
TMEM9B TMEM9 domain family, member B
TNS2 tensin 2
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRIM8 tripartite motif containing 8
UBTF upstream binding transcription factor, RNA polymerase I
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF140 zinc finger protein 140
ZNF146 zinc finger protein 146
ZNF286A zinc finger protein 286A
ZNF672 zinc finger protein 672
ZNHIT2 zinc finger, HIT-type containing 2