trichostatin A-3993 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP2 bone morphogenetic protein 2
CA5B carbonic anhydrase VB, mitochondrial
CD82 CD82 molecule
CDC14B cell division cycle 14B
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DFNB31 deafness, autosomal recessive 31
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EFNB2 ephrin-B2
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPPK1 epiplakin 1
EXT1 exostosin glycosyltransferase 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
GMPR guanosine monophosphate reductase
GSDMB gasdermin B
HOXA1 homeobox A1
IL18R1 interleukin 18 receptor 1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
ITGA7 integrin, alpha 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NMT2 N-myristoyltransferase 2
NPC1 Niemann-Pick disease, type C1
PCDH17 protocadherin 17
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RND1 Rho family GTPase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STOM stomatin
STON1 stonin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
TESK2 testis-specific kinase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIK TRAF2 and NCK interacting kinase
TNS1 tensin 1
TRIM36 tripartite motif containing 36
TRIM9 tripartite motif containing 9
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARSJ arylsulfatase family, member J
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BNC2 basonuclin 2
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC51 coiled-coil domain containing 51
CCDC59 coiled-coil domain containing 59
CCNJL cyclin J-like
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTPS1 CTP synthase 1
CUL1 cullin 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPDC1 DEP domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FAM57A family with sequence similarity 57, member A
FANCC Fanconi anemia, complementation group C
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
FZD8 frizzled class receptor 8
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HMGA2 high mobility group AT-hook 2
HSPB8 heat shock 22kDa protein 8
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INHBB inhibin, beta B
ITPKC inositol-trisphosphate 3-kinase C
KAT6B K(lysine) acetyltransferase 6B
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM4D lysine (K)-specific demethylase 4D
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
MED18 mediator complex subunit 18
MEPCE methylphosphate capping enzyme
METTL4 methyltransferase like 4
NDP Norrie disease (pseudoglioma)
NLRX1 NLR family member X1
NSD1 nuclear receptor binding SET domain protein 1
NUP62 nucleoporin 62kDa
NUPR1 nuclear protein, transcriptional regulator, 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALMD palmdelphin
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLAU plasminogen activator, urokinase
PPAN peter pan homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM23 RNA binding motif protein 23
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN2 Ras and Rab interactor 2
RNF126P1 ring finger protein 126 pseudogene 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMYD5 SMYD family member 5
SOX12 SRY (sex determining region Y)-box 12
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TARBP2 TAR (HIV-1) RNA binding protein 2
TMC5 transmembrane channel-like 5
TMED1 transmembrane emp24 protein transport domain containing 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TSKU tsukushi, small leucine rich proteoglycan
TTC4 tetratricopeptide repeat domain 4
TUBGCP3 tubulin, gamma complex associated protein 3
UBTF upstream binding transcription factor, RNA polymerase I
URGCP upregulator of cell proliferation
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
ZC3H4 zinc finger CCCH-type containing 4
ZFP30 ZFP30 zinc finger protein
ZNF32 zinc finger protein 32
ZSCAN31 zinc finger and SCAN domain containing 31