trichostatin A-3872 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-3872 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACRV1 acrosomal vesicle protein 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AJAP1 adherens junctions associated protein 1
ARC activity-regulated cytoskeleton-associated protein
ARR3 arrestin 3, retinal (X-arrestin)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAX BCL2-associated X protein
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C4BPA complement component 4 binding protein, alpha
CA5B carbonic anhydrase VB, mitochondrial
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CDRT1 CMT1A duplicated region transcript 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
COL16A1 collagen, type XVI, alpha 1
CREBBP CREB binding protein
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DGCR14 DiGeorge syndrome critical region gene 14
DLC1 DLC1 Rho GTPase activating protein
EGR1 early growth response 1
ELOVL5 ELOVL fatty acid elongase 5
FAXDC2 fatty acid hydroxylase domain containing 2
FBXL8 F-box and leucine-rich repeat protein 8
FXYD5 FXYD domain containing ion transport regulator 5
GGT1 gamma-glutamyltransferase 1
GK glycerol kinase
GML glycosylphosphatidylinositol anchored molecule like
GPR137 G protein-coupled receptor 137
GRIK5 glutamate receptor, ionotropic, kainate 5
HAND1 heart and neural crest derivatives expressed 1
HIST1H3B histone cluster 1, H3b
HMGN5 high mobility group nucleosome binding domain 5
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
ICOSLG inducible T-cell co-stimulator ligand
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
ING1 inhibitor of growth family, member 1
INHBE inhibin, beta E
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPK1 inositol-tetrakisphosphate 1-kinase
KIAA1109 KIAA1109
LAT2 linker for activation of T cells family, member 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRP12 low density lipoprotein receptor-related protein 12
MAGOH2P mago-nashi homolog 2, pseudogene
MBD2 methyl-CpG binding domain protein 2
MMP13 matrix metallopeptidase 13
MMP25 matrix metallopeptidase 25
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYOZ1 myozenin 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEUROG2 neurogenin 2
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPY4R neuropeptide Y receptor Y4
OBSL1 obscurin-like 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PARVA parvin, alpha
PDE10A phosphodiesterase 10A
PDPN podoplanin
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP2 plakophilin 2
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSG6 pregnancy specific beta-1-glycoprotein 6
RAB40C RAB40C, member RAS oncogene family
RB1 retinoblastoma 1
RBM5 RNA binding motif protein 5
RECQL5 RecQ protein-like 5
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUSC2 RUN and SH3 domain containing 2
SATB1 SATB homeobox 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SP100 SP100 nuclear antigen
SPTBN5 spectrin, beta, non-erythrocytic 5
SSTR1 somatostatin receptor 1
SSX3 synovial sarcoma, X breakpoint 3
SUN1 Sad1 and UNC84 domain containing 1
TAOK2 TAO kinase 2
TBXA2R thromboxane A2 receptor
TEF thyrotrophic embryonic factor
TERT telomerase reverse transcriptase
TJAP1 tight junction associated protein 1 (peripheral)
TPSG1 tryptase gamma 1
TRIB2 tribbles pseudokinase 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC39A tetratricopeptide repeat domain 39A
YY1 YY1 transcription factor
ZNF230 zinc finger protein 230

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD4 acyl-CoA binding domain containing 4
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ANP32A-IT1 ANP32A intronic transcript 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C17ORF80 chromosome 17 open reading frame 80
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
C4ORF29 chromosome 4 open reading frame 29
CCDC132 coiled-coil domain containing 132
CCDC64 coiled-coil domain containing 64
CCNK cyclin K
CD3D CD3d molecule, delta (CD3-TCR complex)
CD83 CD83 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK6 cyclin-dependent kinase 6
CES3 carboxylesterase 3
CLCN2 chloride channel, voltage-sensitive 2
CLSPN claspin
CSF1R colony stimulating factor 1 receptor
CTC1 CTS telomere maintenance complex component 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPY19L1P1 DPY19L1 pseudogene 1
DRD1 dopamine receptor D1
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
ETAA1 Ewing tumor-associated antigen 1
FAM86C1 family with sequence similarity 86, member C1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKRP fukutin related protein
FLCN folliculin
FLJ11710 uncharacterized protein FLJ11710
FMOD fibromodulin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GID4 GID complex subunit 4
GLB1L galactosidase, beta 1-like
GRTP1 growth hormone regulated TBC protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IL12RB1 interleukin 12 receptor, beta 1
KDM5C lysine (K)-specific demethylase 5C
KLF3 Kruppel-like factor 3 (basic)
KRI1 KRI1 homolog (S. cerevisiae)
KRT13 keratin 13, type I
LMBR1L limb development membrane protein 1-like
LRRC37A3 leucine rich repeat containing 37, member A3
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAOB monoamine oxidase B
MCOLN1 mucolipin 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MUC3A mucin 3A, cell surface associated
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOL10 nucleolar protein 10
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHGA8 protocadherin gamma subfamily A, 8
PLA2G3 phospholipase A2, group III
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODNL1 podocan-like 1
POM121 POM121 transmembrane nucleoporin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTTG3P pituitary tumor-transforming 3, pseudogene
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
REPS2 RALBP1 associated Eps domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SIX1 SIX homeobox 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC44A1 solute carrier family 44 (choline transporter), member 1
SP1 Sp1 transcription factor
STON1 stonin 1
TBC1D19 TBC1 domain family, member 19
TBC1D2 TBC1 domain family, member 2
TEP1 telomerase-associated protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TLR2 toll-like receptor 2
TMEM121 transmembrane protein 121
TMPRSS3 transmembrane protease, serine 3
TOM1 target of myb1 (chicken)
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
USP6NL USP6 N-terminal like
WLS wntless Wnt ligand secretion mediator
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZNF350 zinc finger protein 350
ZNF446 zinc finger protein 446
ZNF669 zinc finger protein 669
ZNF76 zinc finger protein 76