trichostatin A-3791 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3791 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRB2 adhesion G protein-coupled receptor B2
AGTR1 angiotensin II receptor, type 1
APAF1 apoptotic peptidase activating factor 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP6 bone morphogenetic protein 6
CA5B carbonic anhydrase VB, mitochondrial
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFAP69 cilia and flagella associated protein 69
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
FABP4 fatty acid binding protein 4, adipocyte
FHL3 four and a half LIM domains 3
FXYD7 FXYD domain containing ion transport regulator 7
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
H1FX H1 histone family, member X
HOXA1 homeobox A1
IL1RAP interleukin 1 receptor accessory protein
IL7 interleukin 7
IRF6 interferon regulatory factor 6
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDR kinase insert domain receptor
KIF5C kinesin family member 5C
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LUM lumican
MAK male germ cell-associated kinase
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP2K3 mitogen-activated protein kinase kinase 3
MERTK MER proto-oncogene, tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NGF nerve growth factor (beta polypeptide)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PAIP2B poly(A) binding protein interacting protein 2B
PCDH7 protocadherin 7
PCDH9 protocadherin 9
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNCB synuclein, beta
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
STOM stomatin
STON1 stonin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
TJP3 tight junction protein 3
TMPRSS11E transmembrane protease, serine 11E
TPMT thiopurine S-methyltransferase
TPPP tubulin polymerization promoting protein
TRIM36 tripartite motif containing 36
TRIM9 tripartite motif containing 9
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
ANP32A-IT1 ANP32A intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C17ORF53 chromosome 17 open reading frame 53
C19ORF40 chromosome 19 open reading frame 40
C9ORF40 chromosome 9 open reading frame 40
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC106 coiled-coil domain containing 106
CDC7 cell division cycle 7
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CUEDC1 CUE domain containing 1
CUL1 cullin 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DENND2D DENN/MADD domain containing 2D
DEPDC1 DEP domain containing 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DTWD1 DTW domain containing 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FBRS fibrosin
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
HMGB3 high mobility group box 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL7R interleukin 7 receptor
INHBB inhibin, beta B
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF14 kinesin family member 14
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRRC41 leucine rich repeat containing 41
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCOLN3 mucolipin 3
MEPCE methylphosphate capping enzyme
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NLRX1 NLR family member X1
NMI N-myc (and STAT) interactor
NUP62 nucleoporin 62kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PHF11 PHD finger protein 11
PHF14 PHD finger protein 14
PLK1 polo-like kinase 1
PPAN peter pan homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PUS1 pseudouridylate synthase 1
RBM23 RNA binding motif protein 23
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
SUN2 Sad1 and UNC84 domain containing 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TARBP2 TAR (HIV-1) RNA binding protein 2
TRIB3 tribbles pseudokinase 3
UBXN8 UBX domain protein 8
VEGFC vascular endothelial growth factor C
WT1 Wilms tumor 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZFX zinc finger protein, X-linked
ZNF165 zinc finger protein 165
ZNF33B zinc finger protein 33B
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF692 zinc finger protein 692
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF804A zinc finger protein 804A
ZZZ3 zinc finger, ZZ-type containing 3