trichostatin A-3787 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3787 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP6 bone morphogenetic protein 6
CA5B carbonic anhydrase VB, mitochondrial
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMIP cell migration inducing protein, hyaluronan binding
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLDN1 claudin 1
COBL cordon-bleu WH2 repeat protein
COL21A1 collagen, type XXI, alpha 1
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CREB5 cAMP responsive element binding protein 5
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
EPHB3 EPH receptor B3
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FYN FYN proto-oncogene, Src family tyrosine kinase
GBP2 guanylate binding protein 2, interferon-inducible
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
HOXA1 homeobox A1
IL1RAP interleukin 1 receptor accessory protein
IRF6 interferon regulatory factor 6
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLHL25 kelch-like family member 25
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MAP2K3 mitogen-activated protein kinase kinase 3
MERTK MER proto-oncogene, tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PGBD5 piggyBac transposable element derived 5
PGF placental growth factor
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIRT4 sirtuin 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNCB synuclein, beta
SORBS1 sorbin and SH3 domain containing 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
STON1 stonin 1
SYNGR3 synaptogyrin 3
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAGLN3 transgelin 3
TAOK3 TAO kinase 3
TBC1D2 TBC1 domain family, member 2
THEMIS2 thymocyte selection associated family member 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNIK TRAF2 and NCK interacting kinase
TPMT thiopurine S-methyltransferase
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM36 tripartite motif containing 36
TRIM9 tripartite motif containing 9
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX2 armadillo repeat containing, X-linked 2
AURKA aurora kinase A
BCAR3 breast cancer anti-estrogen resistance 3
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC9 coiled-coil domain containing 9
CCNJ cyclin J
CCP110 centriolar coiled coil protein 110kDa
CDC7 cell division cycle 7
CLCF1 cardiotrophin-like cytokine factor 1
CSNK1D casein kinase 1, delta
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEPDC1 DEP domain containing 1
E2F8 E2F transcription factor 8
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FPGS folylpolyglutamate synthase
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL6 interleukin 6
IMPACT impact RWD domain protein
INHBB inhibin, beta B
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LPAR2 lysophosphatidic acid receptor 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MLPH melanophilin
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCS1 neuronal calcium sensor 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRX1 NLR family member X1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NSD1 nuclear receptor binding SET domain protein 1
NUP62 nucleoporin 62kDa
PALMD palmdelphin
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
RBM23 RNA binding motif protein 23
RIN2 Ras and Rab interactor 2
RNF2 ring finger protein 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCAF8 SR-related CTD-associated factor 8
SCGB2A2 secretoglobin, family 2A, member 2
SENP6 SUMO1/sentrin specific peptidase 6
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SIM2 single-minded family bHLH transcription factor 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAGP small cell adhesion glycoprotein
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THRAP3 thyroid hormone receptor associated protein 3
TLR2 toll-like receptor 2
TMED1 transmembrane emp24 protein transport domain containing 1
TRIB3 tribbles pseudokinase 3
TSSC4 tumor suppressing subtransferable candidate 4
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZNF165 zinc finger protein 165
ZNF32 zinc finger protein 32
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF74 zinc finger protein 74
ZNF804A zinc finger protein 804A
ZZZ3 zinc finger, ZZ-type containing 3