trichostatin A-3746 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-3746 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AGTR1 angiotensin II receptor, type 1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP6 bone morphogenetic protein 6
CCL20 chemokine (C-C motif) ligand 20
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEMIP cell migration inducing protein, hyaluronan binding
CNTNAP2 contactin associated protein-like 2
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB3 EPH receptor B3
FABP4 fatty acid binding protein 4, adipocyte
FOS FBJ murine osteosarcoma viral oncogene homolog
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GMPR guanosine monophosphate reductase
H1FX H1 histone family, member X
HAP1 huntingtin-associated protein 1
IL1RAP interleukin 1 receptor accessory protein
IL7 interleukin 7
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
ITGA7 integrin, alpha 7
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
LBH limb bud and heart development
LIFR leukemia inhibitory factor receptor alpha
LMCD1 LIM and cysteine-rich domains 1
LPIN1 lipin 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAPT microtubule-associated protein tau
MERTK MER proto-oncogene, tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PCDH7 protocadherin 7
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PKP2 plakophilin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB6B RAB6B, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNF24 ring finger protein 24
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAP23 synaptosomal-associated protein, 23kDa
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
STON1 stonin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
SYTL2 synaptotagmin-like 2
TJP3 tight junction protein 3
TNIK TRAF2 and NCK interacting kinase
TRIM36 tripartite motif containing 36
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
USP2 ubiquitin specific peptidase 2
ZCCHC14 zinc finger, CCHC domain containing 14

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANP32A-IT1 ANP32A intronic transcript 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP22 Rho GTPase activating protein 22
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL7A B-cell CLL/lymphoma 7A
BNC2 basonuclin 2
BOLA1 bolA family member 1
C19ORF40 chromosome 19 open reading frame 40
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC59 coiled-coil domain containing 59
CCNO cyclin O
CLCF1 cardiotrophin-like cytokine factor 1
COG7 component of oligomeric golgi complex 7
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEPDC1 DEP domain containing 1
ELP6 elongator acetyltransferase complex subunit 6
EXD3 exonuclease 3'-5' domain containing 3
FADD Fas (TNFRSF6)-associated via death domain
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
GMEB2 glucocorticoid modulatory element binding protein 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2I general transcription factor IIi
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL33 interleukin 33
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
INHBB inhibin, beta B
IPP intracisternal A particle-promoted polypeptide
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
LIF leukemia inhibitory factor
LMNB1 lamin B1
LOC100286895 cell division cycle 27 homolog pseudogene
LPAR1 lysophosphatidic acid receptor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MEPCE methylphosphate capping enzyme
MLPH melanophilin
MSL1 male-specific lethal 1 homolog (Drosophila)
NARFL nuclear prelamin A recognition factor-like
NAT6 N-acetyltransferase 6 (GCN5-related)
NOD1 nucleotide-binding oligomerization domain containing 1
NUPR1 nuclear protein, transcriptional regulator, 1
PLK1 polo-like kinase 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PXDC1 PX domain containing 1
RBM23 RNA binding motif protein 23
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SMAGP small cell adhesion glycoprotein
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TSSC4 tumor suppressing subtransferable candidate 4
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZBTB1 zinc finger and BTB domain containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC10 zinc finger, CCHC domain containing 10
ZFP69B ZFP69 zinc finger protein B
ZNF165 zinc finger protein 165
ZNF33B zinc finger protein 33B
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692
ZNF76 zinc finger protein 76
ZNF787 zinc finger protein 787
ZZZ3 zinc finger, ZZ-type containing 3