trichostatin A-3688 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3688 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ANGPTL4 angiopoietin-like 4
APP amyloid beta (A4) precursor protein
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ASMTL acetylserotonin O-methyltransferase-like
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP4 bone morphogenetic protein 4
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CNTNAP2 contactin associated protein-like 2
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTSZ cathepsin Z
CXCR4 chemokine (C-X-C motif) receptor 4
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELOVL4 ELOVL fatty acid elongase 4
EPHB3 EPH receptor B3
EPPK1 epiplakin 1
EXT1 exostosin glycosyltransferase 1
FABP4 fatty acid binding protein 4, adipocyte
FKBP10 FK506 binding protein 10, 65 kDa
FOSL2 FOS-like antigen 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HOXA1 homeobox A1
IRF6 interferon regulatory factor 6
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0040 KIAA0040
KIF5C kinesin family member 5C
LBH limb bud and heart development
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MEGF9 multiple EGF-like-domains 9
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MUC3B mucin 3B, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NGF nerve growth factor (beta polypeptide)
NPM3 nucleophosmin/nucleoplasmin 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PDE4DIP phosphodiesterase 4D interacting protein
PICALM phosphatidylinositol binding clathrin assembly protein
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCD protein kinase C, delta
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RIMS3 regulating synaptic membrane exocytosis 3
RNF24 ring finger protein 24
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIRT4 sirtuin 4
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAI1 snail family zinc finger 1
SNCB synuclein, beta
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
STK16 serine/threonine kinase 16
STON1 stonin 1
SYT1 synaptotagmin I
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
THEMIS2 thymocyte selection associated family member 2
TJP3 tight junction protein 3
TNIK TRAF2 and NCK interacting kinase
TNS1 tensin 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
USP2 ubiquitin specific peptidase 2

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
ARSJ arylsulfatase family, member J
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
C19ORF40 chromosome 19 open reading frame 40
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CDT1 chromatin licensing and DNA replication factor 1
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTCF CCCTC-binding factor (zinc finger protein)
CYTH2 cytohesin 2
DBF4B DBF4 zinc finger B
DCLRE1A DNA cross-link repair 1A
DEPDC1 DEP domain containing 1
E2F8 E2F transcription factor 8
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FADD Fas (TNFRSF6)-associated via death domain
FAM57A family with sequence similarity 57, member A
FOXA1 forkhead box A1
FST follistatin
FZD8 frizzled class receptor 8
GBX2 gastrulation brain homeobox 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPR1 G protein-coupled receptor 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HMGA2 high mobility group AT-hook 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPACT impact RWD domain protein
INHBB inhibin, beta B
IPP intracisternal A particle-promoted polypeptide
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LIF leukemia inhibitory factor
LMNB1 lamin B1
LOC100127972 uncharacterized LOC100127972
LPAR1 lysophosphatidic acid receptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LUC7L2 LUC7-like 2 (S. cerevisiae)
MAGEF1 melanoma antigen family F1
MEPCE methylphosphate capping enzyme
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MTPAP mitochondrial poly(A) polymerase
NLRX1 NLR family member X1
NSD1 nuclear receptor binding SET domain protein 1
NUP62 nucleoporin 62kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN2 Ras and Rab interactor 2
RIPPLY3 ripply transcriptional repressor 3
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SNORA21 small nucleolar RNA, H/ACA box 21
SRSF4 serine/arginine-rich splicing factor 4
STXBP3 syntaxin binding protein 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TRIM13 tripartite motif containing 13
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTC31 tetratricopeptide repeat domain 31
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
WBSCR16 Williams-Beuren syndrome chromosome region 16
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED1 zinc finger, BED-type containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF264 zinc finger protein 264
ZNF652 zinc finger protein 652
ZNF692 zinc finger protein 692
ZNF721 zinc finger protein 721
ZNF804A zinc finger protein 804A
ZZZ3 zinc finger, ZZ-type containing 3