trichostatin A-3566 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-3566 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM20 ADAM metallopeptidase domain 20
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMOT angiomotin
ANO2 anoctamin 2, calcium activated chloride channel
ATF7IP activating transcription factor 7 interacting protein
BCO1 beta-carotene oxygenase 1
BST1 bone marrow stromal cell antigen 1
BUD31 BUD31 homolog (S. cerevisiae)
C19ORF66 chromosome 19 open reading frame 66
CCPG1 cell cycle progression 1
CD52 CD52 molecule
CD53 CD53 molecule
CDC14A cell division cycle 14A
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDRT1 CMT1A duplicated region transcript 1
CLEC4M C-type lectin domain family 4, member M
CLIP2 CAP-GLY domain containing linker protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DEPDC5 DEP domain containing 5
DIXDC1 DIX domain containing 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DSC3 desmocollin 3
DUOX1 dual oxidase 1
E2F5 E2F transcription factor 5, p130-binding
EFS embryonal Fyn-associated substrate
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ETV5 ets variant 5
FAM110D family with sequence similarity 110, member D
FAM149A family with sequence similarity 149, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF5 fibroblast growth factor 5
FGL1 fibrinogen-like 1
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GIPR gastric inhibitory polypeptide receptor
HES2 hes family bHLH transcription factor 2
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMG20B high mobility group 20B
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
IGHA1 immunoglobulin heavy constant alpha 1
IL11 interleukin 11
ITPKA inositol-trisphosphate 3-kinase A
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM4B lysine (K)-specific demethylase 4B
KRIT1 KRIT1, ankyrin repeat containing
KRT31 keratin 31, type I
LMAN1 lectin, mannose-binding, 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MC5R melanocortin 5 receptor
MMP25 matrix metallopeptidase 25
MTCP1 mature T-cell proliferation 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR6A1 nuclear receptor subfamily 6, group A, member 1
OLFML2B olfactomedin-like 2B
OSMR oncostatin M receptor
PALM paralemmin
PDAP1 PDGFA associated protein 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCH2 phospholipase C, eta 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PODXL2 podocalyxin-like 2
POFUT1 protein O-fucosyltransferase 1
POU3F1 POU class 3 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PRAME preferentially expressed antigen in melanoma
PROL1 proline rich, lacrimal 1
RCAN3 RCAN family member 3
RIMS3 regulating synaptic membrane exocytosis 3
RPL23AP53 ribosomal protein L23a pseudogene 53
SAA4 serum amyloid A4, constitutive
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNX13 sorting nexin 13
SPRR1A small proline-rich protein 1A
STATH statherin
SV2A synaptic vesicle glycoprotein 2A
SYNJ2 synaptojanin 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM4 transglutaminase 4
TJAP1 tight junction associated protein 1 (peripheral)
TM4SF1 transmembrane 4 L six family member 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBXN1 UBX domain protein 1
UTS2 urotensin 2
VWA5A von Willebrand factor A domain containing 5A
WDR78 WD repeat domain 78

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AFF4 AF4/FMR2 family, member 4
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ATAD3A ATPase family, AAA domain containing 3A
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
C1ORF159 chromosome 1 open reading frame 159
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX8 chromobox homolog 8
CCDC88C coiled-coil domain containing 88C
CCNO cyclin O
CD82 CD82 molecule
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNGB3 cyclic nucleotide gated channel beta 3
CSTA cystatin A (stefin A)
CTAGE9 CTAGE family, member 9
CUZD1 CUB and zona pellucida-like domains 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DGKE diacylglycerol kinase, epsilon 64kDa
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP2 dual specificity phosphatase 2
E2F1 E2F transcription factor 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF5A2 eukaryotic translation initiation factor 5A2
EPN3 epsin 3
FAM204A family with sequence similarity 204, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGD6 FYVE, RhoGEF and PH domain containing 6
FRK fyn-related Src family tyrosine kinase
FSCN1 fascin actin-bundling protein 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAN gigaxonin
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HIST1H2BF histone cluster 1, H2bf
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KIAA0319L KIAA0319-like
KLF7 Kruppel-like factor 7 (ubiquitous)
LAMA5 laminin, alpha 5
LARP6 La ribonucleoprotein domain family, member 6
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRP2 low density lipoprotein receptor-related protein 2
LUZP1 leucine zipper protein 1
MAGEA6 melanoma antigen family A6
MED15 mediator complex subunit 15
METTL2B methyltransferase like 2B
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NIPAL2 NIPA-like domain containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NT5DC3 5'-nucleotidase domain containing 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PPOX protoporphyrinogen oxidase
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTDSS2 phosphatidylserine synthase 2
PTPRE protein tyrosine phosphatase, receptor type, E
QTRT1 queuine tRNA-ribosyltransferase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF141 ring finger protein 141
RNF43 ring finger protein 43
RPGRIP1L RPGRIP1-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SIRT6 sirtuin 6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPIDR scaffolding protein involved in DNA repair
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STBD1 starch binding domain 1
STIM1 stromal interaction molecule 1
SULT4A1 sulfotransferase family 4A, member 1
SYT17 synaptotagmin XVII
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TET3 tet methylcytosine dioxygenase 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM53 transmembrane protein 53
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTBK2 tau tubulin kinase 2
VWA1 von Willebrand factor A domain containing 1
XK X-linked Kx blood group
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF10 zinc finger protein 10
ZNF219 zinc finger protein 219
ZNF408 zinc finger protein 408
ZNF669 zinc finger protein 669
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747