trichostatin A-3510 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3510 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ANG angiogenin, ribonuclease, RNase A family, 5
APLP1 amyloid beta (A4) precursor-like protein 1
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
C16ORF45 chromosome 16 open reading frame 45
C19ORF66 chromosome 19 open reading frame 66
CA5B carbonic anhydrase VB, mitochondrial
CCDC88A coiled-coil domain containing 88A
CD83 CD83 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CTIF CBP80/20-dependent translation initiation factor
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPF1 D4, zinc and double PHD fingers family 1
DPYSL4 dihydropyrimidinase-like 4
DUSP10 dual specificity phosphatase 10
EDA ectodysplasin A
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
EPHB2 EPH receptor B2
FAM182B family with sequence similarity 182, member B
FAM214B family with sequence similarity 214, member B
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
HEG1 heart development protein with EGF-like domains 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
JAG1 jagged 1
KIAA0513 KIAA0513
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
KRAS Kirsten rat sarcoma viral oncogene homolog
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMD monocyte to macrophage differentiation-associated
NAP1L3 nucleosome assembly protein 1-like 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NXPE3 neurexophilin and PC-esterase domain family, member 3
OASL 2'-5'-oligoadenylate synthetase-like
OLFML2A olfactomedin-like 2A
PADI3 peptidyl arginine deiminase, type III
PGBD5 piggyBac transposable element derived 5
PLAC1 placenta-specific 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRPH peripherin
RAI2 retinoic acid induced 2
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNDC3B RUN domain containing 3B
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SP110 SP110 nuclear body protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
SYBU syntabulin (syntaxin-interacting)
TMCC2 transmembrane and coiled-coil domain family 2
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
YPEL1 yippee-like 1 (Drosophila)
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADCY6 adenylate cyclase 6
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C19ORF40 chromosome 19 open reading frame 40
C9ORF91 chromosome 9 open reading frame 91
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDT1 chromatin licensing and DNA replication factor 1
CISH cytokine inducible SH2-containing protein
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CXCL12 chemokine (C-X-C motif) ligand 12
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DTYMK deoxythymidylate kinase (thymidylate kinase)
EGR3 early growth response 3
ELMO3 engulfment and cell motility 3
ESRP2 epithelial splicing regulatory protein 2
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FPGS folylpolyglutamate synthase
GID4 GID complex subunit 4
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2IRD1 GTF2I repeat domain containing 1
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LAMA3 laminin, alpha 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MBTD1 mbt domain containing 1
MEPCE methylphosphate capping enzyme
METTL2B methyltransferase like 2B
METTL8 methyltransferase like 8
MSL1 male-specific lethal 1 homolog (Drosophila)
MXD3 MAX dimerization protein 3
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OGFRL1 opioid growth factor receptor-like 1
POGK pogo transposable element with KRAB domain
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRNP prion protein
PRR3 proline rich 3
PTPRU protein tyrosine phosphatase, receptor type, U
PUS1 pseudouridylate synthase 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM4B RNA binding motif protein 4B
RIPPLY3 ripply transcriptional repressor 3
RNH1 ribonuclease/angiogenin inhibitor 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCRN1 secernin 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SMG9 SMG9 nonsense mediated mRNA decay factor
SPAG7 sperm associated antigen 7
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
STK16 serine/threonine kinase 16
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TGFB3 transforming growth factor, beta 3
THEM6 thioesterase superfamily member 6
TNS3 tensin 3
TRABD TraB domain containing
TRIB3 tribbles pseudokinase 3
TSSC4 tumor suppressing subtransferable candidate 4
UBXN6 UBX domain protein 6
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF428 zinc finger protein 428
ZNF668 zinc finger protein 668
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZZZ3 zinc finger, ZZ-type containing 3