trichostatin A-3332 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the trichostatin A-3332 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRD2 adhesion G protein-coupled receptor D2
ADRA1B adrenoceptor alpha 1B
AHNAK2 AHNAK nucleoprotein 2
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
AUTS2 autism susceptibility candidate 2
BAIAP3 BAI1-associated protein 3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAP29 B-cell receptor-associated protein 29
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BTF3P11 basic transcription factor 3 pseudogene 11
C21ORF2 chromosome 21 open reading frame 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCNA1 cyclin A1
CD4 CD4 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDHR2 cadherin-related family member 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
COL17A1 collagen, type XVII, alpha 1
CRYM crystallin, mu
CYB5A cytochrome b5 type A (microsomal)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPYSL4 dihydropyrimidinase-like 4
EDA ectodysplasin A
EPYC epiphycan
ERC2-IT1 ERC2 intronic transcript 1
ERO1LB ERO1-like beta (S. cerevisiae)
EXOSC1 exosome component 1
FBXO21 F-box protein 21
FYN FYN proto-oncogene, Src family tyrosine kinase
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GP5 glycoprotein V (platelet)
GP6 glycoprotein VI (platelet)
GRK5 G protein-coupled receptor kinase 5
HAB1 B1 for mucin
HBB hemoglobin, beta
HEG1 heart development protein with EGF-like domains 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HNF4A hepatocyte nuclear factor 4, alpha
HRH1 histamine receptor H1
IFI6 interferon, alpha-inducible protein 6
IGLJ3 immunoglobulin lambda joining 3
KIF21B kinesin family member 21B
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MUC3B mucin 3B, cell surface associated
NME5 NME/NM23 family member 5
OBSL1 obscurin-like 1
PICK1 protein interacting with PRKCA 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLA2G1B phospholipase A2, group IB (pancreas)
PLIN2 perilipin 2
PRDX2 peroxiredoxin 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRPH peripherin
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAB6B RAB6B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RPL23AP53 ribosomal protein L23a pseudogene 53
RRBP1 ribosome binding protein 1
SARM1 sterile alpha and TIR motif containing 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3D21 SH3 domain containing 21
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SYCE1L synaptonemal complex central element protein 1-like
SYT11 synaptotagmin XI
TAS2R10 taste receptor, type 2, member 10
TBXA2R thromboxane A2 receptor
TMCC2 transmembrane and coiled-coil domain family 2
TMEM63A transmembrane protein 63A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TSNAXIP1 translin-associated factor X interacting protein 1
TTC38 tetratricopeptide repeat domain 38
WDTC1 WD and tetratricopeptide repeats 1
YY2 YY2 transcription factor
ZDHHC14 zinc finger, DHHC-type containing 14

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
BCAR3 breast cancer anti-estrogen resistance 3
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRD9 bromodomain containing 9
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C14ORF93 chromosome 14 open reading frame 93
C19ORF54 chromosome 19 open reading frame 54
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCNO cyclin O
CEP97 centrosomal protein 97kDa
CPTP ceramide-1-phosphate transfer protein
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EFNA1 ephrin-A1
EGFL7 EGF-like-domain, multiple 7
ERCC4 excision repair cross-complementation group 4
FAIM Fas apoptotic inhibitory molecule
FBXO5 F-box protein 5
FPGS folylpolyglutamate synthase
FZD3 frizzled class receptor 3
GALK1 galactokinase 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLS2 glutaminase 2 (liver, mitochondrial)
IFT140 intraflagellar transport 140
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF1 interferon regulatory factor 1
IRX4 iroquois homeobox 4
ITPKB inositol-trisphosphate 3-kinase B
KAT2A K(lysine) acetyltransferase 2A
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
KLHL25 kelch-like family member 25
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHX6 LIM homeobox 6
LMBR1L limb development membrane protein 1-like
LOC257152 uncharacterized LOC257152
MATK megakaryocyte-associated tyrosine kinase
METTL8 methyltransferase like 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTG1 mitochondrial ribosome-associated GTPase 1
NHEJ1 nonhomologous end-joining factor 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PBLD phenazine biosynthesis-like protein domain containing
PCDHGB5 protocadherin gamma subfamily B, 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRR15L proline rich 15-like
PTBP2 polypyrimidine tract binding protein 2
RAB5B RAB5B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM42 RNA binding motif protein 42
RIN2 Ras and Rab interactor 2
RIPPLY3 ripply transcriptional repressor 3
ROM1 retinal outer segment membrane protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIDT1 SID1 transmembrane family, member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMYD5 SMYD family member 5
SND1-IT1 SND1 intronic transcript 1
SPIDR scaffolding protein involved in DNA repair
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULF1 sulfatase 1
THOP1 thimet oligopeptidase 1
TMEM183A transmembrane protein 183A
TOM1 target of myb1 (chicken)
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN1 tetraspanin 1
UFSP2 UFM1-specific peptidase 2
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VAV1 vav 1 guanine nucleotide exchange factor
WBP1L WW domain binding protein 1-like
XYLT2 xylosyltransferase II
YAP1 Yes-associated protein 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF586 zinc finger protein 586
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862