trichostatin A-332 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-332 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABHD3 abhydrolase domain containing 3
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
AQP3 aquaporin 3 (Gill blood group)
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATG13 autophagy related 13
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAIAP3 BAI1-associated protein 3
BIK BCL2-interacting killer (apoptosis-inducing)
C7ORF43 chromosome 7 open reading frame 43
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP76 centrosomal protein 76kDa
CFAP20 cilia and flagella associated protein 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CRY1 cryptochrome circadian clock 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DRP2 dystrophin related protein 2
DUS2 dihydrouridine synthase 2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EHD1 EH-domain containing 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPOR erythropoietin receptor
FAM214B family with sequence similarity 214, member B
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GLRX glutaredoxin (thioltransferase)
GM2A GM2 ganglioside activator
GMCL1 germ cell-less, spermatogenesis associated 1
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRK5 G protein-coupled receptor kinase 5
H1F0 H1 histone family, member 0
HIST1H2AG histone cluster 1, H2ag
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSDL2 hydroxysteroid dehydrogenase like 2
HSPA2 heat shock 70kDa protein 2
IFITM1 interferon induced transmembrane protein 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIF5C kinesin family member 5C
KIFAP3 kinesin-associated protein 3
KLHL25 kelch-like family member 25
LGALS1 lectin, galactoside-binding, soluble, 1
LPPR2 lipid phosphate phosphatase-related protein type 2
LUZP1 leucine zipper protein 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MFSD12 major facilitator superfamily domain containing 12
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MYO9B myosin IXB
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NOSIP nitric oxide synthase interacting protein
OMG oligodendrocyte myelin glycoprotein
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI3 peptidyl arginine deiminase, type III
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PGRMC2 progesterone receptor membrane component 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITPNA phosphatidylinositol transfer protein, alpha
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PTRF polymerase I and transcript release factor
RAB40B RAB40B, member RAS oncogene family
RNF24 ring finger protein 24
RNFT1 ring finger protein, transmembrane 1
RNFT2 ring finger protein, transmembrane 2
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SECISBP2L SECIS binding protein 2-like
SERINC5 serine incorporator 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SWAP70 SWAP switching B-cell complex 70kDa subunit
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
VRK3 vaccinia related kinase 3
WDR47 WD repeat domain 47
ZCCHC24 zinc finger, CCHC domain containing 24
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACVR2B activin A receptor, type IIB
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
ALX1 ALX homeobox 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BATF basic leucine zipper transcription factor, ATF-like
BHMT betaine--homocysteine S-methyltransferase
BTBD2 BTB (POZ) domain containing 2
C1ORF159 chromosome 1 open reading frame 159
CA11 carbonic anhydrase XI
CALHM2 calcium homeostasis modulator 2
CAPN15 calpain 15
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CCNL2 cyclin L2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHD2 chromodomain helicase DNA binding protein 2
CLCN6 chloride channel, voltage-sensitive 6
COG7 component of oligomeric golgi complex 7
CRYAB crystallin, alpha B
CTCF CCCTC-binding factor (zinc finger protein)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP22 dual specificity phosphatase 22
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EDA2R ectodysplasin A2 receptor
ERO1L ERO1-like (S. cerevisiae)
ESRP2 epithelial splicing regulatory protein 2
EXOSC10 exosome component 10
FOXD1 forkhead box D1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GPR21 G protein-coupled receptor 21
GTF2I general transcription factor IIi
HBD hemoglobin, delta
HDAC7 histone deacetylase 7
HIRIP3 HIRA interacting protein 3
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KEAP1 kelch-like ECH-associated protein 1
LIAS lipoic acid synthetase
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MEPCE methylphosphate capping enzyme
MEPE matrix extracellular phosphoglycoprotein
METTL8 methyltransferase like 8
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMRN2 multimerin 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCKAP1L NCK-associated protein 1-like
NIPAL2 NIPA-like domain containing 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NUP62 nucleoporin 62kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PFAS phosphoribosylformylglycinamidine synthase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POGK pogo transposable element with KRAB domain
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTDSS2 phosphatidylserine synthase 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMYD5 SMYD family member 5
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SURF2 surfeit 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGM5 transglutaminase 5
TMEM176A transmembrane protein 176A
TMPRSS5 transmembrane protease, serine 5
TNS3 tensin 3
TRIB3 tribbles pseudokinase 3
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
WDR13 WD repeat domain 13
XBP1 X-box binding protein 1
ZFHX3 zinc finger homeobox 3
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZXDC ZXD family zinc finger C