trichostatin A-3312 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-3312 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ARMCX2 armadillo repeat containing, X-linked 2
BBS9 Bardet-Biedl syndrome 9
CA5B carbonic anhydrase VB, mitochondrial
CCDC28A coiled-coil domain containing 28A
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EGR1 early growth response 1
ELOVL4 ELOVL fatty acid elongase 4
FAM105A family with sequence similarity 105, member A
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRAMD1C GRAM domain containing 1C
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL21R interleukin 21 receptor
ITM2C integral membrane protein 2C
KIAA0513 KIAA0513
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMD monocyte to macrophage differentiation-associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NUP62CL nucleoporin 62kDa C-terminal like
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PCDH9 protocadherin 9
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PRPH peripherin
RAI2 retinoic acid induced 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STK17A serine/threonine kinase 17a
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TMSB15A thymosin beta 15a
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACVR2B activin A receptor, type IIB
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AKAP8 A kinase (PRKA) anchor protein 8
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CCNO cyclin O
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTAGE9 CTAGE family, member 9
CTCF CCCTC-binding factor (zinc finger protein)
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DOLPP1 dolichyldiphosphatase 1
EFNA1 ephrin-A1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HOXC11 homeobox C11
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL16 methyltransferase like 16
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RIPPLY3 ripply transcriptional repressor 3
SFMBT1 Scm-like with four mbt domains 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TNS3 tensin 3
TOR3A torsin family 3, member A
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBXN8 UBX domain protein 8
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2