trichostatin A-3243 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3243 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ANG angiogenin, ribonuclease, RNase A family, 5
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP7A ATPase, Cu++ transporting, alpha polypeptide
CASC1 cancer susceptibility candidate 1
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
FAM105A family with sequence similarity 105, member A
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
H1F0 H1 histone family, member 0
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
INSIG1 insulin induced gene 1
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0513 KIAA0513
KIFAP3 kinesin-associated protein 3
LIMA1 LIM domain and actin binding 1
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NME5 NME/NM23 family member 5
NME7 NME/NM23 family member 7
NUP62CL nucleoporin 62kDa C-terminal like
NXN nucleoredoxin
NXPE3 neurexophilin and PC-esterase domain family, member 3
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PCDH9 protocadherin 9
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRPH peripherin
RAI2 retinoic acid induced 2
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
SYT11 synaptotagmin XI
TMEM45A transmembrane protein 45A
TMSB15A thymosin beta 15a
TRIM2 tripartite motif containing 2
TSPAN5 tetraspanin 5
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
VWA5A von Willebrand factor A domain containing 5A
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BANP BTG3 associated nuclear protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF35 chromosome 1 open reading frame 35
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHKB choline kinase beta
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTCF CCCTC-binding factor (zinc finger protein)
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
GABPB1 GA binding protein transcription factor, beta subunit 1
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIRIP3 HIRA interacting protein 3
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL1 male-specific lethal 1 homolog (Drosophila)
MYD88 myeloid differentiation primary response 88
NARFL nuclear prelamin A recognition factor-like
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RGS19 regulator of G-protein signaling 19
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SFMBT1 Scm-like with four mbt domains 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SOX12 SRY (sex determining region Y)-box 12
SREK1 splicing regulatory glutamine/lysine-rich protein 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC2 stanniocalcin 2
THBS3 thrombospondin 3
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
UNKL unkempt family zinc finger-like
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF282 zinc finger protein 282
ZNF652 zinc finger protein 652
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2