trichostatin A-3227 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-3227 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL4 angiopoietin-like 4
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BEX1 brain expressed, X-linked 1
BMP7 bone morphogenetic protein 7
C19ORF66 chromosome 19 open reading frame 66
CA5B carbonic anhydrase VB, mitochondrial
CASC1 cancer susceptibility candidate 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GPX1 glutathione peroxidase 1
GRK5 G protein-coupled receptor kinase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IQCG IQ motif containing G
KIAA0513 KIAA0513
KIF21B kinesin family member 21B
LAT2 linker for activation of T cells family, member 2
LDHB lactate dehydrogenase B
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
LYZ lysozyme
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MMD monocyte to macrophage differentiation-associated
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSN moesin
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NME5 NME/NM23 family member 5
NSUN6 NOP2/Sun domain family, member 6
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLLP plasmolipin
PRPH peripherin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNDC3B RUN domain containing 3B
S100A8 S100 calcium binding protein A8
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNAI2 snail family zinc finger 2
SORBS1 sorbin and SH3 domain containing 1
SRGN serglycin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TRAFD1 TRAF-type zinc finger domain containing 1
TSPAN5 tetraspanin 5
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADCY6 adenylate cyclase 6
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C9ORF40 chromosome 9 open reading frame 40
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CENPO centromere protein O
CNGB3 cyclic nucleotide gated channel beta 3
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
EFNA1 ephrin-A1
EGR3 early growth response 3
ERBB2IP erbb2 interacting protein
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL4R interleukin 4 receptor
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
LMNB1 lamin B1
LRRC41 leucine rich repeat containing 41
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHB3 protocadherin beta 3
PDGFA platelet-derived growth factor alpha polypeptide
POGK pogo transposable element with KRAB domain
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC35F2 solute carrier family 35, member F2
SNHG3 small nucleolar RNA host gene 3
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
XBP1 X-box binding protein 1
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2