trichostatin A-3177 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-3177 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOB aldolase B, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
APLP1 amyloid beta (A4) precursor-like protein 1
ARG1 arginase 1
BMP7 bone morphogenetic protein 7
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
COL6A1 collagen, type VI, alpha 1
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYLD cylindromatosis (turban tumor syndrome)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DLX4 distal-less homeobox 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP10 dual specificity phosphatase 10
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EAF2 ELL associated factor 2
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPOR erythropoietin receptor
ETV5 ets variant 5
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GIPR gastric inhibitory polypeptide receptor
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
HAMP hepcidin antimicrobial peptide
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RN interleukin 1 receptor antagonist
KIAA0040 KIAA0040
KIAA0513 KIAA0513
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
MAP1B microtubule-associated protein 1B
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAST3 microtubule associated serine/threonine kinase 3
MBNL2 muscleblind-like splicing regulator 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MITF microphthalmia-associated transcription factor
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MMD monocyte to macrophage differentiation-associated
NEK1 NIMA-related kinase 1
PADI3 peptidyl arginine deiminase, type III
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMEL premelanosome protein
PRPH peripherin
PSD4 pleckstrin and Sec7 domain containing 4
PTRF polymerase I and transcript release factor
RAI2 retinoic acid induced 2
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
SCG2 secretogranin II
SCML1 sex comb on midleg-like 1 (Drosophila)
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SNAI2 snail family zinc finger 2
SNN stannin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
TGFBR3 transforming growth factor, beta receptor III
THEMIS2 thymocyte selection associated family member 2
TMEM45A transmembrane protein 45A
TRAFD1 TRAF-type zinc finger domain containing 1
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
VIPR1 vasoactive intestinal peptide receptor 1
WNT2B wingless-type MMTV integration site family, member 2B
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BANP BTG3 associated nuclear protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF30 chromosome 11 open reading frame 30
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CCNO cyclin O
CDC7 cell division cycle 7
CHKB choline kinase beta
COIL coilin
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIRIP3 HIRA interacting protein 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KEAP1 kelch-like ECH-associated protein 1
KPTN kaptin (actin binding protein)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LDHB lactate dehydrogenase B
LMNB1 lamin B1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYZ lysozyme
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MEX3C mex-3 RNA binding family member C
MON1B MON1 secretory trafficking family member B
MSL1 male-specific lethal 1 homolog (Drosophila)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NME6 NME/NM23 nucleoside diphosphate kinase 6
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDGFA platelet-derived growth factor alpha polypeptide
PP14571 uncharacterized LOC100130449
PPT2 palmitoyl-protein thioesterase 2
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCRN1 secernin 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SETDB1 SET domain, bifurcated 1
SFMBT1 Scm-like with four mbt domains 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMYD5 SMYD family member 5
SNHG3 small nucleolar RNA host gene 3
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRGN serglycin
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STC2 stanniocalcin 2
TET3 tet methylcytosine dioxygenase 3
TMEM62 transmembrane protein 62
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
UBL4A ubiquitin-like 4A
UBXN8 UBX domain protein 8
WBSCR16 Williams-Beuren syndrome chromosome region 16
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF573 zinc finger protein 573
ZNF768 zinc finger protein 768
ZNF787 zinc finger protein 787