trichostatin A-3114 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-3114 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACP6 acid phosphatase 6, lysophosphatidic
AMDHD2 amidohydrolase domain containing 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPT1 angiopoietin 1
AOX1 aldehyde oxidase 1
ARG2 arginase 2
ARHGAP35 Rho GTPase activating protein 35
BIK BCL2-interacting killer (apoptosis-inducing)
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CCDC132 coiled-coil domain containing 132
CD226 CD226 molecule
CD247 CD247 molecule
CD59 CD59 molecule, complement regulatory protein
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP41 centrosomal protein 41kDa
CPM carboxypeptidase M
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL3 dihydropyrimidinase-like 3
DSP desmoplakin
DTNB dystrobrevin, beta
ECI2 enoyl-CoA delta isomerase 2
EFNA4 ephrin-A4
EIF5A2 eukaryotic translation initiation factor 5A2
ELL2 elongation factor, RNA polymerase II, 2
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
ETV1 ets variant 1
F12 coagulation factor XII (Hageman factor)
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FST follistatin
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GAL3ST4 galactose-3-O-sulfotransferase 4
GATA6 GATA binding protein 6
GPR153 G protein-coupled receptor 153
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
ICAM1 intercellular adhesion molecule 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KIF5C kinesin family member 5C
MARCKS myristoylated alanine-rich protein kinase C substrate
MID1 midline 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPZL1 myelin protein zero-like 1
MREG melanoregulin
MRPS12 mitochondrial ribosomal protein S12
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAM1 neural cell adhesion molecule 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRCAM neuronal cell adhesion molecule
PALLD palladin, cytoskeletal associated protein
PCDH9 protocadherin 9
PCGF2 polycomb group ring finger 2
PEX1 peroxisomal biogenesis factor 1
PFN2 profilin 2
PLCG1 phospholipase C, gamma 1
PLS1 plastin 1
PLSCR3 phospholipid scramblase 3
PMP22 peripheral myelin protein 22
POU4F1 POU class 4 homeobox 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROM1 prominin 1
PRR5L proline rich 5 like
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRB protein tyrosine phosphatase, receptor type, B
REPS2 RALBP1 associated Eps domain containing 2
RGS14 regulator of G-protein signaling 14
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCE sarcoglycan, epsilon
SHB Src homology 2 domain containing adaptor protein B
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SRR serine racemase
TCHH trichohyalin
TECPR2 tectonin beta-propeller repeat containing 2
TEX40 testis expressed 40
TMEM255A transmembrane protein 255A
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNIK TRAF2 and NCK interacting kinase
TPD52L1 tumor protein D52-like 1
TPMT thiopurine S-methyltransferase
TRIM2 tripartite motif containing 2
TRIM58 tripartite motif containing 58
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TSPAN4 tetraspanin 4
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
WLS wntless Wnt ligand secretion mediator
ZMYND11 zinc finger, MYND-type containing 11
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF105 chromosome 1 open reading frame 105
C8ORF60 chromosome 8 open reading frame 60
CLTCL1 clathrin, heavy chain-like 1
CTAGE9 CTAGE family, member 9
CTSO cathepsin O
CXCL2 chemokine (C-X-C motif) ligand 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXD3 exonuclease 3'-5' domain containing 3
FAM50B family with sequence similarity 50, member B
FBXL15 F-box and leucine-rich repeat protein 15
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GLRA1 glycine receptor, alpha 1
GPX2 glutathione peroxidase 2
GRAMD4 GRAM domain containing 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1B histone cluster 1, H1b
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H3G histone cluster 1, H3g
INCENP inner centromere protein antigens 135/155kDa
ISOC2 isochorismatase domain containing 2
JMJD4 jumonji domain containing 4
KLF13 Kruppel-like factor 13
LIMD2 LIM domain containing 2
LOC729164 hCG1732469
LRRK1 leucine-rich repeat kinase 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGOHB mago-nashi homolog B (Drosophila)
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MOGS mannosyl-oligosaccharide glucosidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NINJ2 ninjurin 2
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NR1D2 nuclear receptor subfamily 1, group D, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLTP phospholipid transfer protein
POM121L2 POM121 transmembrane nucleoporin-like 2
PUS1 pseudouridylate synthase 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RBM15B RNA binding motif protein 15B
RFPL1S RFPL1 antisense RNA 1
RHOBTB1 Rho-related BTB domain containing 1
RNF121 ring finger protein 121
RNH1 ribonuclease/angiogenin inhibitor 1
RPP40 ribonuclease P/MRP 40kDa subunit
SCD5 stearoyl-CoA desaturase 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SENP7 SUMO1/sentrin specific peptidase 7
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC10A3 solute carrier family 10, member 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMR3A submaxillary gland androgen regulated protein 3A
SNHG20 small nucleolar RNA host gene 20
SOGA1 suppressor of glucose, autophagy associated 1
SPATA20 spermatogenesis associated 20
SPI1 Spi-1 proto-oncogene
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TESK1 testis-specific kinase 1
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS4 thrombospondin 4
TIGD6 tigger transposable element derived 6
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM19 transmembrane protein 19
TMEM212 transmembrane protein 212
TRAF2 TNF receptor-associated factor 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBE2O ubiquitin-conjugating enzyme E2O
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
WNT16 wingless-type MMTV integration site family, member 16
YY2 YY2 transcription factor
ZBTB3 zinc finger and BTB domain containing 3
ZBTB38 zinc finger and BTB domain containing 38
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF41 zinc finger protein 41
ZNF592 zinc finger protein 592