trichostatin A-3077 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-3077 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD6 abhydrolase domain containing 6
AMIGO2 adhesion molecule with Ig-like domain 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMC9 armadillo repeat containing 9
ASB9 ankyrin repeat and SOCS box containing 9
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BIK BCL2-interacting killer (apoptosis-inducing)
BLVRA biliverdin reductase A
BMP6 bone morphogenetic protein 6
CCDC181 coiled-coil domain containing 181
CCDC92 coiled-coil domain containing 92
CD1A CD1a molecule
CD59 CD59 molecule, complement regulatory protein
CDR2L cerebellar degeneration-related protein 2-like
CHN2 chimerin 2
CPM carboxypeptidase M
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPEP2 dipeptidase 2
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
ECI2 enoyl-CoA delta isomerase 2
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ETV1 ets variant 1
EXPH5 exophilin 5
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR1 fibroblast growth factor receptor 1
FOXD1 forkhead box D1
GCH1 GTP cyclohydrolase 1
H1F0 H1 histone family, member 0
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA9 homeobox A9
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
KLF4 Kruppel-like factor 4 (gut)
LHX2 LIM homeobox 2
LOC730101 uncharacterized LOC730101
MAK male germ cell-associated kinase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4 microtubule-associated protein 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MPZL1 myelin protein zero-like 1
MSI1 musashi RNA-binding protein 1
MXD4 MAX dimerization protein 4
MYH10 myosin, heavy chain 10, non-muscle
MYO6 myosin VI
NCAM1 neural cell adhesion molecule 1
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT2 N-myristoyltransferase 2
NRF1 nuclear respiratory factor 1
NRP1 neuropilin 1
PAX5 paired box 5
PCDH9 protocadherin 9
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PFKM phosphofructokinase, muscle
PFN2 profilin 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
SATB1 SATB homeobox 1
SCAMP5 secretory carrier membrane protein 5
SCARB2 scavenger receptor class B, member 2
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCE sarcoglycan, epsilon
SH3D21 SH3 domain containing 21
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STARD13 StAR-related lipid transfer (START) domain containing 13
STX2 syntaxin 2
SV2A synaptic vesicle glycoprotein 2A
TDO2 tryptophan 2,3-dioxygenase
TMEM255A transmembrane protein 255A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1
TRA T cell receptor alpha locus
TRIM2 tripartite motif containing 2
TSGA10 testis specific, 10
TSPAN13 tetraspanin 13
TTC38 tetratricopeptide repeat domain 38
UBTD1 ubiquitin domain containing 1
UNC13B unc-13 homolog B (C. elegans)
UST uronyl-2-sulfotransferase
ZC3H13 zinc finger CCCH-type containing 13
ZNF259P1 zinc finger protein 259 pseudogene 1

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ADI1 acireductone dioxygenase 1
AEN apoptosis enhancing nuclease
ANKRD55 ankyrin repeat domain 55
ARG1 arginase 1
CAPN15 calpain 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD14 CD14 molecule
CDCP1 CUB domain containing protein 1
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFP complement factor properdin
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLTCL1 clathrin, heavy chain-like 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CXCR2 chemokine (C-X-C motif) receptor 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND2D DENN/MADD domain containing 2D
DYSF dysferlin
ERCC2 excision repair cross-complementation group 2
ERCC6L excision repair cross-complementation group 6-like
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM127B family with sequence similarity 127, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FES FES proto-oncogene, tyrosine kinase
FGL1 fibrinogen-like 1
FMNL1 formin-like 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR132 G protein-coupled receptor 132
GSDMD gasdermin D
GTPBP6 GTP binding protein 6 (putative)
HIST1H2BJ histone cluster 1, H2bj
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
ITPKC inositol-trisphosphate 3-kinase C
KIF24 kinesin family member 24
KPTN kaptin (actin binding protein)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
MANSC1 MANSC domain containing 1
MB myoglobin
MBNL3 muscleblind-like splicing regulator 3
MEFV Mediterranean fever
MLPH melanophilin
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRPL12 mitochondrial ribosomal protein L12
MRPL44 mitochondrial ribosomal protein L44
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCS1 neuronal calcium sensor 1
NINJ2 ninjurin 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCNT pericentrin
PDE12 phosphodiesterase 12
PEF1 penta-EF-hand domain containing 1
PIDD1 p53-induced death domain protein 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PMF1 polyamine-modulated factor 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCAN3 RCAN family member 3
RGS19 regulator of G-protein signaling 19
RNF25 ring finger protein 25
SCGB2A2 secretoglobin, family 2A, member 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SCO2 SCO2 cytochrome c oxidase assembly protein
SETD1A SET domain containing 1A
SHPK sedoheptulokinase
SIGLEC15 sialic acid binding Ig-like lectin 15
SKI SKI proto-oncogene
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SPI1 Spi-1 proto-oncogene
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TDRD3 tudor domain containing 3
THOC6 THO complex 6
TMED1 transmembrane emp24 protein transport domain containing 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TOE1 target of EGR1, member 1 (nuclear)
TPM3 tropomyosin 3
TRAF1 TNF receptor-associated factor 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC27 tetratricopeptide repeat domain 27
UBXN8 UBX domain protein 8
UNC93B1 unc-93 homolog B1 (C. elegans)
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813
ZNHIT2 zinc finger, HIT-type containing 2