trichostatin A-3058 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-3058 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACTN2 actinin, alpha 2
ADGRL2 adhesion G protein-coupled receptor L2
ADRB1 adrenoceptor beta 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANG angiogenin, ribonuclease, RNase A family, 5
APOA1 apolipoprotein A-I
AR androgen receptor
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
C9ORF116 chromosome 9 open reading frame 116
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDO1 cysteine dioxygenase type 1
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLGN calmegin
CREB3L1 cAMP responsive element binding protein 3-like 1
CSRP2 cysteine and glycine-rich protein 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM3 dynamin 3
DUSP4 dual specificity phosphatase 4
DZIP3 DAZ interacting zinc finger protein 3
EFNB2 ephrin-B2
ELOVL4 ELOVL fatty acid elongase 4
EPAS1 endothelial PAS domain protein 1
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
ETV1 ets variant 1
FAM49A family with sequence similarity 49, member A
FOXO1 forkhead box O1
FZD3 frizzled class receptor 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCH1 GTP cyclohydrolase 1
GLP1R glucagon-like peptide 1 receptor
GRM4 glutamate receptor, metabotropic 4
GTPBP1 GTP binding protein 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HNMT histamine N-methyltransferase
HOXA1 homeobox A1
HOXA7 homeobox A7
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNA6 interferon, alpha 6
IL1A interleukin 1, alpha
IL1RN interleukin 1 receptor antagonist
IL36RN interleukin 36 receptor antagonist
KALRN kalirin, RhoGEF kinase
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
KLC2 kinesin light chain 2
KLHL22 kelch-like family member 22
LHX2 LIM homeobox 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MED25 mediator complex subunit 25
MLF1 myeloid leukemia factor 1
MMP19 matrix metallopeptidase 19
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTCP1 mature T-cell proliferation 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYLK myosin light chain kinase
NBEA neurobeachin
NF1 neurofibromin 1
NRAP nebulin-related anchoring protein
NRG1 neuregulin 1
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PFN2 profilin 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTHLH parathyroid hormone-like hormone
RAB26 RAB26, member RAS oncogene family
RAD51B RAD51 paralog B
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHO rhodopsin
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPTBN5 spectrin, beta, non-erythrocytic 5
STON1 stonin 1
TCAF1 TRPM8 channel-associated factor 1
TLR7 toll-like receptor 7
TMEM255A transmembrane protein 255A
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TSPY1 testis specific protein, Y-linked 1
TUBB2A tubulin, beta 2A class IIa
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADORA3 adenosine A3 receptor
ADTRP androgen-dependent TFPI-regulating protein
AIM2 absent in melanoma 2
ANKRD55 ankyrin repeat domain 55
ANKRD7 ankyrin repeat domain 7
ARHGAP10 Rho GTPase activating protein 10
ARMC6 armadillo repeat containing 6
ATG10 autophagy related 10
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BHMT2 betaine--homocysteine S-methyltransferase 2
C11ORF21 chromosome 11 open reading frame 21
C1QB complement component 1, q subcomponent, B chain
C3ORF18 chromosome 3 open reading frame 18
CAMKMT calmodulin-lysine N-methyltransferase
CD300C CD300c molecule
CDK3 cyclin-dependent kinase 3
CDY1 chromodomain protein, Y-linked, 1
CENPO centromere protein O
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC4E C-type lectin domain family 4, member E
CNGB3 cyclic nucleotide gated channel beta 3
CST4 cystatin S
DGKG diacylglycerol kinase, gamma 90kDa
DOK3 docking protein 3
DTX2 deltex 2, E3 ubiquitin ligase
EMILIN2 elastin microfibril interfacer 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FMOD fibromodulin
FRMD1 FERM domain containing 1
FXN frataxin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GTPBP6 GTP binding protein 6 (putative)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1B histone cluster 1, H1b
HIST1H2BC histone cluster 1, H2bc
HIST2H2AA3 histone cluster 2, H2aa3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL3RA interleukin 3 receptor, alpha (low affinity)
INCENP inner centromere protein antigens 135/155kDa
IPO4 importin 4
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0408 KIAA0408
KPTN kaptin (actin binding protein)
LOC100286895 cell division cycle 27 homolog pseudogene
LY6G6C lymphocyte antigen 6 complex, locus G6C
MRPL44 mitochondrial ribosomal protein L44
MYBPH myosin binding protein H
NOL10 nucleolar protein 10
NPY4R neuropeptide Y receptor Y4
NTN1 netrin 1
OMG oligodendrocyte myelin glycoprotein
PARP12 poly (ADP-ribose) polymerase family, member 12
PDE8B phosphodiesterase 8B
PDLIM1 PDZ and LIM domain 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
POLH polymerase (DNA directed), eta
PRMT7 protein arginine methyltransferase 7
PTCD1 pentatricopeptide repeat domain 1
REC8 REC8 meiotic recombination protein
RHOB ras homolog family member B
RPL23AP32 ribosomal protein L23a pseudogene 32
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETD1A SET domain containing 1A
SH2D4A SH2 domain containing 4A
SLC35F6 solute carrier family 35, member F6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMR3B submaxillary gland androgen regulated protein 3B
SPATA20 spermatogenesis associated 20
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAR steroidogenic acute regulatory protein
STXBP5L syntaxin binding protein 5-like
SYNDIG1 synapse differentiation inducing 1
TBKBP1 TBK1 binding protein 1
TFDP3 transcription factor Dp family, member 3
TFF2 trefoil factor 2
THBS4 thrombospondin 4
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TONSL tonsoku-like, DNA repair protein
TTC30A tetratricopeptide repeat domain 30A
USP53 ubiquitin specific peptidase 53
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
ZNF16 zinc finger protein 16
ZNF219 zinc finger protein 219
ZNF41 zinc finger protein 41
ZNF492 zinc finger protein 492
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76