trichostatin A-2904 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-2904 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRL2 adhesion G protein-coupled receptor L2
AMIGO2 adhesion molecule with Ig-like domain 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANO10 anoctamin 10
ARG2 arginase 2
ARMC9 armadillo repeat containing 9
ASRGL1 asparaginase like 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BIN1 bridging integrator 1
BLVRA biliverdin reductase A
C5ORF45 chromosome 5 open reading frame 45
CCDC132 coiled-coil domain containing 132
CD59 CD59 molecule, complement regulatory protein
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CECR1 cat eye syndrome chromosome region, candidate 1
CLCN4 chloride channel, voltage-sensitive 4
CLGN calmegin
CPM carboxypeptidase M
CRELD1 cysteine-rich with EGF-like domains 1
CSRP2 cysteine and glycine-rich protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNS cystinosin, lysosomal cystine transporter
CTSV cathepsin V
CXADR coxsackie virus and adenovirus receptor
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDAH2 dimethylarginine dimethylaminohydrolase 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DSP desmoplakin
EFNA4 ephrin-A4
ELOVL4 ELOVL fatty acid elongase 4
ETV1 ets variant 1
EXPH5 exophilin 5
F11R F11 receptor
FAM49A family with sequence similarity 49, member A
FAM69A family with sequence similarity 69, member A
FDXR ferredoxin reductase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXD1 forkhead box D1
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GIPC1 GIPC PDZ domain containing family, member 1
GLRX glutaredoxin (thioltransferase)
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GRAMD3 GRAM domain containing 3
HOXA9 homeobox A9
HSPA2 heat shock 70kDa protein 2
INA internexin neuronal intermediate filament protein, alpha
KIAA0040 KIAA0040
KIAA0226L KIAA0226-like
KIF3C kinesin family member 3C
KIF5C kinesin family member 5C
LEF1 lymphoid enhancer-binding factor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMA1 LIM domain and actin binding 1
MAMLD1 mastermind-like domain containing 1
MARCKS myristoylated alanine-rich protein kinase C substrate
METTL7A methyltransferase like 7A
MPZL1 myelin protein zero-like 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH10 myosin, heavy chain 10, non-muscle
NCAM1 neural cell adhesion molecule 1
NCOR2 nuclear receptor corepressor 2
NLRP1 NLR family, pyrin domain containing 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PALLD palladin, cytoskeletal associated protein
PDE4DIP phosphodiesterase 4D interacting protein
PEX11A peroxisomal biogenesis factor 11 alpha
PFN2 profilin 2
PGBD5 piggyBac transposable element derived 5
PLS1 plastin 1
PLXNA3 plexin A3
PMP22 peripheral myelin protein 22
POU4F1 POU class 4 homeobox 1
POU5F1B POU class 5 homeobox 1B
POU6F1 POU class 6 homeobox 1
RAB26 RAB26, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCE sarcoglycan, epsilon
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT4 signal transducer and activator of transcription 4
TMEM255A transmembrane protein 255A
TPD52L1 tumor protein D52-like 1
TPH1 tryptophan hydroxylase 1
TPM1 tropomyosin 1 (alpha)
TSPAN13 tetraspanin 13
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
ARID5A AT rich interactive domain 5A (MRF1-like)
ARRB1 arrestin, beta 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AVEN apoptosis, caspase activation inhibitor
BAHCC1 BAH domain and coiled-coil containing 1
BPI bactericidal/permeability-increasing protein
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C7ORF43 chromosome 7 open reading frame 43
CARD9 caspase recruitment domain family, member 9
CD320 CD320 molecule
CHMP6 charged multivesicular body protein 6
CLTCL1 clathrin, heavy chain-like 1
CXORF21 chromosome X open reading frame 21
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDN dendrin
DEPDC5 DEP domain containing 5
DGAT1 diacylglycerol O-acyltransferase 1
DPH2 DPH2 homolog (S. cerevisiae)
DTWD1 DTW domain containing 1
ECHDC2 enoyl CoA hydratase domain containing 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM204A family with sequence similarity 204, member A
FES FES proto-oncogene, tyrosine kinase
FGL1 fibrinogen-like 1
FGL2 fibrinogen-like 2
FHL3 four and a half LIM domains 3
FPGS folylpolyglutamate synthase
GEMIN4 gem (nuclear organelle) associated protein 4
HIST1H2BI histone cluster 1, H2bi
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFRD2 interferon-related developmental regulator 2
ISOC2 isochorismatase domain containing 2
KCTD15 potassium channel tetramerization domain containing 15
KRI1 KRI1 homolog (S. cerevisiae)
KRT8P12 keratin 8 pseudogene 12
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIN7B lin-7 homolog B (C. elegans)
LMNB1 lamin B1
LNPEP leucyl/cystinyl aminopeptidase
LOC157562 uncharacterized LOC157562
LRRK1 leucine-rich repeat kinase 1
MATK megakaryocyte-associated tyrosine kinase
METTL1 methyltransferase like 1
METTL16 methyltransferase like 16
MX1 MX dynamin-like GTPase 1
MYBPH myosin binding protein H
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOL10 nucleolar protein 10
NOP2 NOP2 nucleolar protein
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRBP1 nuclear receptor binding protein 1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP12 poly (ADP-ribose) polymerase family, member 12
PBLD phenazine biosynthesis-like protein domain containing
PEMT phosphatidylethanolamine N-methyltransferase
PGP phosphoglycolate phosphatase
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G15 phospholipase A2, group XV
PMFBP1 polyamine modulated factor 1 binding protein 1
PRR14L proline rich 14-like
PRR4 proline rich 4 (lacrimal)
PTGES2 prostaglandin E synthase 2
PUS1 pseudouridylate synthase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RFPL1S RFPL1 antisense RNA 1
RHOB ras homolog family member B
RNH1 ribonuclease/angiogenin inhibitor 1
SKI SKI proto-oncogene
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNHG3 small nucleolar RNA host gene 3
TBXAS1 thromboxane A synthase 1 (platelet)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM39B transmembrane protein 39B
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOE1 target of EGR1, member 1 (nuclear)
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC27 tetratricopeptide repeat domain 27
UNC93B1 unc-93 homolog B1 (C. elegans)
UNG uracil-DNA glycosylase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP36 ubiquitin specific peptidase 36
XAF1 XIAP associated factor 1
ZBTB3 zinc finger and BTB domain containing 3
ZBTB48 zinc finger and BTB domain containing 48
ZNHIT2 zinc finger, HIT-type containing 2