trichostatin A-2881 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-2881 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ANG angiogenin, ribonuclease, RNase A family, 5
APAF1 apoptotic peptidase activating factor 1
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BIRC3 baculoviral IAP repeat containing 3
BST2 bone marrow stromal cell antigen 2
BTN2A2 butyrophilin, subfamily 2, member A2
CA5B carbonic anhydrase VB, mitochondrial
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELL2 elongation factor, RNA polymerase II, 2
ELOVL4 ELOVL fatty acid elongase 4
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GRK5 G protein-coupled receptor kinase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
ITM2C integral membrane protein 2C
KIAA0513 KIAA0513
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
KLHL24 kelch-like family member 24
LARP6 La ribonucleoprotein domain family, member 6
LIMA1 LIM domain and actin binding 1
LIMCH1 LIM and calponin homology domains 1
LYST lysosomal trafficking regulator
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MITF microphthalmia-associated transcription factor
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MVP major vault protein
NME5 NME/NM23 family member 5
NR4A3 nuclear receptor subfamily 4, group A, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLLP plasmolipin
PMEL premelanosome protein
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTRF polymerase I and transcript release factor
RAI2 retinoic acid induced 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RNFT1 ring finger protein, transmembrane 1
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SRPX sushi-repeat containing protein, X-linked
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
TMOD2 tropomodulin 2 (neuronal)
TUBA4A tubulin, alpha 4a
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WSCD1 WSC domain containing 1
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF230 zinc finger protein 230

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACVR2B activin A receptor, type IIB
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
AXIN1 axin 1
B9D2 B9 protein domain 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C14ORF93 chromosome 14 open reading frame 93
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHKB choline kinase beta
CLK1 CDC-like kinase 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDRGK1 DDRGK domain containing 1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVPL envoplakin
FAM57A family with sequence similarity 57, member A
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
GTPBP8 GTP-binding protein 8 (putative)
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LRRC41 leucine rich repeat containing 41
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MBTD1 mbt domain containing 1
MCM9 minichromosome maintenance complex component 9
MCRS1 microspherule protein 1
MDM4 MDM4, p53 regulator
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL16 methyltransferase like 16
MSL1 male-specific lethal 1 homolog (Drosophila)
MTA2 metastasis associated 1 family, member 2
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
PHEX phosphate regulating endopeptidase homolog, X-linked
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPAN peter pan homolog (Drosophila)
PTPRU protein tyrosine phosphatase, receptor type, U
QSER1 glutamine and serine rich 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SFMBT1 Scm-like with four mbt domains 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLTM SAFB-like, transcription modulator
SMAGP small cell adhesion glycoprotein
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
STC2 stanniocalcin 2
TGFB3 transforming growth factor, beta 3
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM254 transmembrane protein 254
TMPRSS3 transmembrane protease, serine 3
TPTE transmembrane phosphatase with tensin homology
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
USP16 ubiquitin specific peptidase 16
USP36 ubiquitin specific peptidase 36
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBTB3 zinc finger and BTB domain containing 3
ZIC1 Zic family member 1
ZNF668 zinc finger protein 668
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2
ZZZ3 zinc finger, ZZ-type containing 3