trichostatin A-2694 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-2694 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSF2 acyl-CoA synthetase family member 2
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMDHD2 amidohydrolase domain containing 2
ANG angiogenin, ribonuclease, RNase A family, 5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AREG amphiregulin
ARG2 arginase 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC9 armadillo repeat containing 9
ASMTL acetylserotonin O-methyltransferase-like
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BBS1 Bardet-Biedl syndrome 1
C9ORF116 chromosome 9 open reading frame 116
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP70 centrosomal protein 70kDa
CREB3 cAMP responsive element binding protein 3
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CXADR coxsackie virus and adenovirus receptor
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAAM1 dishevelled associated activator of morphogenesis 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EFNA4 ephrin-A4
EFNB2 ephrin-B2
ELOVL4 ELOVL fatty acid elongase 4
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
FAM49A family with sequence similarity 49, member A
FGF9 fibroblast growth factor 9
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GMPR guanosine monophosphate reductase
GRK5 G protein-coupled receptor kinase 5
H1F0 H1 histone family, member 0
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IFI6 interferon, alpha-inducible protein 6
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA0226 KIAA0226
KIAA0513 KIAA0513
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
LRRC6 leucine rich repeat containing 6
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK4 MAP/microtubule affinity-regulating kinase 4
MAST3 microtubule associated serine/threonine kinase 3
MCOLN1 mucolipin 1
MPZL1 myelin protein zero-like 1
MTSS1 metastasis suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCAM1 neural cell adhesion molecule 1
NEU1 sialidase 1 (lysosomal sialidase)
NPC1 Niemann-Pick disease, type C1
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PEX1 peroxisomal biogenesis factor 1
PFN2 profilin 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLS1 plastin 1
POLB polymerase (DNA directed), beta
POU4F1 POU class 4 homeobox 1
RFPL3S RFPL3 antisense
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNFT2 ring finger protein, transmembrane 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A44 solute carrier family 25, member 44
SNN stannin
SRR serine racemase
STXBP1 syntaxin binding protein 1
TESK2 testis-specific kinase 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPMT thiopurine S-methyltransferase
TRIM2 tripartite motif containing 2
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TULP3 tubby like protein 3
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZC2HC1A zinc finger, C2HC-type containing 1A
ZSCAN16 zinc finger and SCAN domain containing 16
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
APOBR apolipoprotein B receptor
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B4 ATPase, class I, type 8B, member 4
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C11ORF21 chromosome 11 open reading frame 21
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CLEC5A C-type lectin domain family 5, member A
CTCF CCCTC-binding factor (zinc finger protein)
CTPS1 CTP synthase 1
CTPS2 CTP synthase 2
CUL1 cullin 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
DENND2D DENN/MADD domain containing 2D
DOK2 docking protein 2, 56kDa
DTWD1 DTW domain containing 1
ECHDC2 enoyl CoA hydratase domain containing 2
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ERF Ets2 repressor factor
ETV6 ets variant 6
FAM216A family with sequence similarity 216, member A
FAR2 fatty acyl CoA reductase 2
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GFI1 growth factor independent 1 transcription repressor
GPR18 G protein-coupled receptor 18
GPR183 G protein-coupled receptor 183
GTF2I general transcription factor IIi
HMHA1 histocompatibility (minor) HA-1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INHBE inhibin, beta E
JADE1 jade family PHD finger 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KLF11 Kruppel-like factor 11
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRK1 leucine-rich repeat kinase 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MCM9 minichromosome maintenance complex component 9
MEIS2 Meis homeobox 2
MEPCE methylphosphate capping enzyme
METTL18 methyltransferase like 18
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2 nuclear factor, erythroid 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NTSR1 neurotensin receptor 1 (high affinity)
PARP8 poly (ADP-ribose) polymerase family, member 8
PEF1 penta-EF-hand domain containing 1
PLAU plasminogen activator, urokinase
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRDM13 PR domain containing 13
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF8 serine/arginine-rich splicing factor 8
TARP TCR gamma alternate reading frame protein
TFEC transcription factor EC
TGIF1 TGFB-induced factor homeobox 1
TGM5 transglutaminase 5
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM156 transmembrane protein 156
TNF tumor necrosis factor
TRAC T cell receptor alpha constant
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TRIM8 tripartite motif containing 8
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC33 tetratricopeptide repeat domain 33
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
UCK2 uridine-cytidine kinase 2
WBSCR16 Williams-Beuren syndrome chromosome region 16
WT1 Wilms tumor 1
WT1-AS WT1 antisense RNA
XAF1 XIAP associated factor 1
ZNF32 zinc finger protein 32
ZNF573 zinc finger protein 573
ZNF787 zinc finger protein 787
ZNF804A zinc finger protein 804A
ZNF813 zinc finger protein 813