trichostatin A-2523 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-2523 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACP6 acid phosphatase 6, lysophosphatidic
ACRV1 acrosomal vesicle protein 1
AGFG2 ArfGAP with FG repeats 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BIN1 bridging integrator 1
BLVRA biliverdin reductase A
CCSER2 coiled-coil serine-rich protein 2
CD59 CD59 molecule, complement regulatory protein
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CPNE3 copine III
CRAT carnitine O-acetyltransferase
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSV cathepsin V
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DFNA5 deafness, autosomal dominant 5
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNASE2 deoxyribonuclease II, lysosomal
DUSP4 dual specificity phosphatase 4
DZIP3 DAZ interacting zinc finger protein 3
EFNB2 ephrin-B2
EPS8L3 EPS8-like 3
F11R F11 receptor
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FXYD6 FXYD domain containing ion transport regulator 6
GAB1 GRB2-associated binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GK3P glycerol kinase 3 pseudogene
GM2A GM2 ganglioside activator
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRPR gastrin-releasing peptide receptor
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HCG4B HLA complex group 4B (non-protein coding)
HEG1 heart development protein with EGF-like domains 1
HNF1B HNF1 homeobox B
HOXA1 homeobox A1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFT27 intraflagellar transport 27
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRS4 insulin receptor substrate 4
KIAA1109 KIAA1109
LDHC lactate dehydrogenase C
MAB21L1 mab-21-like 1 (C. elegans)
MAP2K6 mitogen-activated protein kinase kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MEF2C myocyte enhancer factor 2C
MKL2 MKL/myocardin-like 2
MPZL1 myelin protein zero-like 1
MTCP1 mature T-cell proliferation 1
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCAM1 neural cell adhesion molecule 1
NDNF neuron-derived neurotrophic factor
NTN1 netrin 1
PADI1 peptidyl arginine deiminase, type I
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX5 paired box 5
PCDH9 protocadherin 9
PCNXL2 pecanex-like 2 (Drosophila)
PCSK5 proprotein convertase subtilisin/kexin type 5
PDE4DIP phosphodiesterase 4D interacting protein
PFN2 profilin 2
PLCG1 phospholipase C, gamma 1
PLS1 plastin 1
PLS3 plastin 3
POU4F1 POU class 4 homeobox 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PVR poliovirus receptor
PXN paxillin
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
REC8 REC8 meiotic recombination protein
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RTCA RNA 3'-terminal phosphate cyclase
SIGLEC8 sialic acid binding Ig-like lectin 8
SIX2 SIX homeobox 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STAT4 signal transducer and activator of transcription 4
STON1 stonin 1
TLR7 toll-like receptor 7
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TPD52L1 tumor protein D52-like 1
TPST1 tyrosylprotein sulfotransferase 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRD T cell receptor delta locus
TSPAN13 tetraspanin 13
TUFT1 tuftelin 1
UBTD1 ubiquitin domain containing 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSL4 acyl-CoA synthetase long-chain family member 4
ADGRE2 adhesion G protein-coupled receptor E2
ADI1 acireductone dioxygenase 1
ALS2CL ALS2 C-terminal like
ANKRD40 ankyrin repeat domain 40
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC6 armadillo repeat containing 6
ASB7 ankyrin repeat and SOCS box containing 7
ASCC1 activating signal cointegrator 1 complex subunit 1
ATAD3A ATPase family, AAA domain containing 3A
C1ORF109 chromosome 1 open reading frame 109
C2CD2 C2 calcium-dependent domain containing 2
C8ORF33 chromosome 8 open reading frame 33
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN1 calpain 1, (mu/I) large subunit
CCDC106 coiled-coil domain containing 106
CCDC86 coiled-coil domain containing 86
CD320 CD320 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CLCF1 cardiotrophin-like cytokine factor 1
COL4A2 collagen, type IV, alpha 2
CPQ carboxypeptidase Q
CTPS1 CTP synthase 1
CTSO cathepsin O
CYSLTR1 cysteinyl leukotriene receptor 1
DDN dendrin
DENND2D DENN/MADD domain containing 2D
DEPDC1 DEP domain containing 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DOK3 docking protein 3
DSPP dentin sialophosphoprotein
FAM136A family with sequence similarity 136, member A
GTPBP6 GTP binding protein 6 (putative)
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2BI histone cluster 1, H2bi
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
INF2 inverted formin, FH2 and WH2 domain containing
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPO4 importin 4
IPO8 importin 8
IRF8 interferon regulatory factor 8
KAT2A K(lysine) acetyltransferase 2A
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KRT81 keratin 81, type II
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIMD2 LIM domain containing 2
LIME1 Lck interacting transmembrane adaptor 1
LIN7A lin-7 homolog A (C. elegans)
LMNB2 lamin B2
LRRK1 leucine-rich repeat kinase 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MCM9 minichromosome maintenance complex component 9
MCRS1 microspherule protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL2B methyltransferase like 2B
NABP2 nucleic acid binding protein 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NOL6 nucleolar protein 6 (RNA-associated)
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
PBLD phenazine biosynthesis-like protein domain containing
PEMT phosphatidylethanolamine N-methyltransferase
PFAS phosphoribosylformylglycinamidine synthase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCH pro-melanin-concentrating hormone
POLM polymerase (DNA directed), mu
PRMT3 protein arginine methyltransferase 3
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPL13P5 ribosomal protein L13 pseudogene 5
RRP1 ribosomal RNA processing 1
SECISBP2 SECIS binding protein 2
SGMS1 sphingomyelin synthase 1
SIL1 SIL1 nucleotide exchange factor
SLC10A3 solute carrier family 10, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
SREBF1 sterol regulatory element binding transcription factor 1
TERT telomerase reverse transcriptase
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPK1 thiamin pyrophosphokinase 1
ULK1 unc-51 like autophagy activating kinase 1
UPB1 ureidopropionase, beta
USP19 ubiquitin specific peptidase 19
VEGFB vascular endothelial growth factor B
VILL villin-like
ZBTB10 zinc finger and BTB domain containing 10
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZSCAN31 zinc finger and SCAN domain containing 31