trichostatin A-2137 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-2137 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM28 ADAM metallopeptidase domain 28
ADGRL1 adhesion G protein-coupled receptor L1
ADGRL2 adhesion G protein-coupled receptor L2
AMIGO2 adhesion molecule with Ig-like domain 2
ANG angiogenin, ribonuclease, RNase A family, 5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC9 armadillo repeat containing 9
ATP13A2 ATPase type 13A2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
BMP6 bone morphogenetic protein 6
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF66 chromosome 19 open reading frame 66
CCDC92 coiled-coil domain containing 92
CD59 CD59 molecule, complement regulatory protein
CDR2L cerebellar degeneration-related protein 2-like
CFAP69 cilia and flagella associated protein 69
CLIP2 CAP-GLY domain containing linker protein 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPTP ceramide-1-phosphate transfer protein
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DDAH2 dimethylarginine dimethylaminohydrolase 2
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DOCK6 dedicator of cytokinesis 6
DSP desmoplakin
ECI2 enoyl-CoA delta isomerase 2
EFNA4 ephrin-A4
EFNB2 ephrin-B2
EPAS1 endothelial PAS domain protein 1
ETV1 ets variant 1
EXPH5 exophilin 5
FAM65A family with sequence similarity 65, member A
FGF9 fibroblast growth factor 9
FNBP1L formin binding protein 1-like
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
ICAM5 intercellular adhesion molecule 5, telencephalin
ITGA7 integrin, alpha 7
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIAA0040 KIAA0040
KIF5C kinesin family member 5C
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LHX2 LIM homeobox 2
LIN7B lin-7 homolog B (C. elegans)
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MEF2C myocyte enhancer factor 2C
MKL2 MKL/myocardin-like 2
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MNX1 motor neuron and pancreas homeobox 1
MPZL1 myelin protein zero-like 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYO1B myosin IB
NCAM1 neural cell adhesion molecule 1
NDNF neuron-derived neurotrophic factor
NOTCH4 notch 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
OLFML2A olfactomedin-like 2A
PADI2 peptidyl arginine deiminase, type II
PALLD palladin, cytoskeletal associated protein
PCDH17 protocadherin 17
PCDH9 protocadherin 9
PCNXL2 pecanex-like 2 (Drosophila)
PDGFRL platelet-derived growth factor receptor-like
PFN2 profilin 2
PGAP1 post-GPI attachment to proteins 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
PORCN porcupine homolog (Drosophila)
POU4F1 POU class 4 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYCRL pyrroline-5-carboxylate reductase-like
RAB26 RAB26, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPL13P5 ribosomal protein L13 pseudogene 5
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SGCE sarcoglycan, epsilon
STON1 stonin 1
SV2A synaptic vesicle glycoprotein 2A
TBC1D2 TBC1 domain family, member 2
THAP10 THAP domain containing 10
TJAP1 tight junction associated protein 1 (peripheral)
TMEM255A transmembrane protein 255A
TPD52L1 tumor protein D52-like 1
TPMT thiopurine S-methyltransferase
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADI1 acireductone dioxygenase 1
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
APOL6 apolipoprotein L, 6
ARRB1 arrestin, beta 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AVEN apoptosis, caspase activation inhibitor
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BPI bactericidal/permeability-increasing protein
BRIX1 BRX1, biogenesis of ribosomes
C1ORF159 chromosome 1 open reading frame 159
C22ORF46 chromosome 22 open reading frame 46
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC186 coiled-coil domain containing 186
CCDC86 coiled-coil domain containing 86
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CENPT centromere protein T
CES3 carboxylesterase 3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLCF1 cardiotrophin-like cytokine factor 1
CLEC4E C-type lectin domain family 4, member E
COMMD10 COMM domain containing 10
DDN dendrin
DEAF1 DEAF1 transcription factor
DENND2D DENN/MADD domain containing 2D
DEPTOR DEP domain containing MTOR-interacting protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERN2 endoplasmic reticulum to nucleus signaling 2
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FXN frataxin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR22 G protein-coupled receptor 22
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HMGB3P1 high mobility group box 3 pseudogene 1
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDM5C lysine (K)-specific demethylase 5C
KLK5 kallikrein-related peptidase 5
KPTN kaptin (actin binding protein)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LPPR3 lipid phosphate phosphatase-related protein type 3
LRP5 low density lipoprotein receptor-related protein 5
MAGEF1 melanoma antigen family F1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL2B methyltransferase like 2B
MOCS3 molybdenum cofactor synthesis 3
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NAT6 N-acetyltransferase 6 (GCN5-related)
NCS1 neuronal calcium sensor 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL10 nucleolar protein 10
NTSR1 neurotensin receptor 1 (high affinity)
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OXCT2 3-oxoacid CoA transferase 2
PARPBP PARP1 binding protein
PMCH pro-melanin-concentrating hormone
PPCS phosphopantothenoylcysteine synthetase
PRICKLE3 prickle homolog 3 (Drosophila)
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB13 RAB13, member RAS oncogene family
RNFT1 ring finger protein, transmembrane 1
RPL10L ribosomal protein L10-like
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAGLN transgelin
TCTN2 tectonic family member 2
TGFBR1 transforming growth factor, beta receptor 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM212 transmembrane protein 212
TMEM254 transmembrane protein 254
TRIM25 tripartite motif containing 25
TTC27 tetratricopeptide repeat domain 27
TWSG1 twisted gastrulation BMP signaling modulator 1
UCK2 uridine-cytidine kinase 2
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFB vascular endothelial growth factor B
VNN2 vanin 2
ZBTB38 zinc finger and BTB domain containing 38
ZBTB6 zinc finger and BTB domain containing 6
ZNF675 zinc finger protein 675
ZNF749 zinc finger protein 749
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN5A zinc finger and SCAN domain containing 5A