trichostatin A-1951 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-1951 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADRB2 adrenoceptor beta 2, surface
AGTPBP1 ATP/GTP binding protein 1
AHNAK2 AHNAK nucleoprotein 2
AKAP13 A kinase (PRKA) anchor protein 13
ALAS1 5'-aminolevulinate synthase 1
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
C2CD2L C2CD2-like
CCDC68 coiled-coil domain containing 68
CCL20 chemokine (C-C motif) ligand 20
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DAAM1 dishevelled associated activator of morphogenesis 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DOPEY1 dopey family member 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB2 ephrin-B2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMP1 epithelial membrane protein 1
ETV5 ets variant 5
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FBXO3 F-box protein 3
FLRT3 fibronectin leucine rich transmembrane protein 3
FYN FYN proto-oncogene, Src family tyrosine kinase
GCDH glutaryl-CoA dehydrogenase
GLRX glutaredoxin (thioltransferase)
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KDM4B lysine (K)-specific demethylase 4B
KIAA0513 KIAA0513
LAMP3 lysosomal-associated membrane protein 3
LMCD1 LIM and cysteine-rich domains 1
LPIN1 lipin 1
LRRC1 leucine rich repeat containing 1
MAP2K3 mitogen-activated protein kinase kinase 3
MEF2C myocyte enhancer factor 2C
MMP1 matrix metallopeptidase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NFIL3 nuclear factor, interleukin 3 regulated
OASL 2'-5'-oligoadenylate synthetase-like
PAIP2B poly(A) binding protein interacting protein 2B
PKP2 plakophilin 2
PLSCR4 phospholipid scramblase 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPL periplakin
PRKCD protein kinase C, delta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB3A RAB3A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RNF24 ring finger protein 24
SDC4 syndecan 4
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3GL3 SH3-domain GRB2-like 3
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMOX spermine oxidase
SQLE squalene epoxidase
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TAOK3 TAO kinase 3
TBPL1 TBP-like 1
TPMT thiopurine S-methyltransferase
TPST2 tyrosylprotein sulfotransferase 2
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AMIGO2 adhesion molecule with Ig-like domain 2
ANAPC10 anaphase promoting complex subunit 10
ANKRD40 ankyrin repeat domain 40
ATF1 activating transcription factor 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BMI1 BMI1 proto-oncogene, polycomb ring finger
BPTF bromodomain PHD finger transcription factor
BRIX1 BRX1, biogenesis of ribosomes
C2CD5 C2 calcium-dependent domain containing 5
CBR3 carbonyl reductase 3
CCDC51 coiled-coil domain containing 51
CCDC59 coiled-coil domain containing 59
CDC7 cell division cycle 7
CLCF1 cardiotrophin-like cytokine factor 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
DBF4 DBF4 zinc finger
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
E2F8 E2F transcription factor 8
FADD Fas (TNFRSF6)-associated via death domain
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FPGS folylpolyglutamate synthase
FST follistatin
GIN1 gypsy retrotransposon integrase 1
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
HMGB2 high mobility group box 2
IL7R interleukin 7 receptor
INHBB inhibin, beta B
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KEAP1 kelch-like ECH-associated protein 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MEPCE methylphosphate capping enzyme
MOCOS molybdenum cofactor sulfurase
MRPS2 mitochondrial ribosomal protein S2
NCOA6 nuclear receptor coactivator 6
NDC80 NDC80 kinetochore complex component
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NOL11 nucleolar protein 11
NUP62 nucleoporin 62kDa
PCTP phosphatidylcholine transfer protein
PEF1 penta-EF-hand domain containing 1
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM22 RNA binding motif protein 22
RBM23 RNA binding motif protein 23
RBM39 RNA binding motif protein 39
REPIN1 replication initiator 1
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAF8 SR-related CTD-associated factor 8
SCO2 SCO2 cytochrome c oxidase assembly protein
SETD1B SET domain containing 1B
SNUPN snurportin 1
SPOP speckle-type POZ protein
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCERG1 transcription elongation regulator 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THUMPD1 THUMP domain containing 1
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM168 transmembrane protein 168
TMEM185B transmembrane protein 185B
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM13 tripartite motif containing 13
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UNC50 unc-50 homolog (C. elegans)
USP16 ubiquitin specific peptidase 16
VEGFC vascular endothelial growth factor C
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
XBP1 X-box binding protein 1
YEATS2 YEATS domain containing 2
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF532 zinc finger protein 532
ZNF672 zinc finger protein 672
ZZZ3 zinc finger, ZZ-type containing 3