trichostatin A-1793 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-1793 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP26 Rho GTPase activating protein 26
ARID5B AT rich interactive domain 5B (MRF1-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVPI1 arginine vasopressin-induced 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOPEY1 dopey family member 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
F11R F11 receptor
FABP4 fatty acid binding protein 4, adipocyte
FLRT3 fibronectin leucine rich transmembrane protein 3
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GLRX glutaredoxin (thioltransferase)
GMCL1 germ cell-less, spermatogenesis associated 1
GMPR guanosine monophosphate reductase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL1RAP interleukin 1 receptor accessory protein
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KIF5C kinesin family member 5C
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPIN1 lipin 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAT2A methionine adenosyltransferase II, alpha
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP1 matrix metallopeptidase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIL3 nuclear factor, interleukin 3 regulated
PCDH9 protocadherin 9
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKCD protein kinase C, delta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RNF24 ring finger protein 24
SH3GL3 SH3-domain GRB2-like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STOM stomatin
SYT1 synaptotagmin I
SYTL2 synaptotagmin-like 2
TAOK3 TAO kinase 3
TNIK TRAF2 and NCK interacting kinase
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ADCY7 adenylate cyclase 7
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BCAR3 breast cancer anti-estrogen resistance 3
BRIX1 BRX1, biogenesis of ribosomes
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEPDC1 DEP domain containing 1
EXOSC10 exosome component 10
FADD Fas (TNFRSF6)-associated via death domain
FAIM Fas apoptotic inhibitory molecule
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GBX2 gastrulation brain homeobox 2
GLMN glomulin, FKBP associated protein
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
INHBB inhibin, beta B
IRF9 interferon regulatory factor 9
JADE1 jade family PHD finger 1
KAT5 K(lysine) acetyltransferase 5
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MISP mitotic spindle positioning
MSL2 male-specific lethal 2 homolog (Drosophila)
MTPAP mitochondrial poly(A) polymerase
MX1 MX dynamin-like GTPase 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NSD1 nuclear receptor binding SET domain protein 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP62 nucleoporin 62kDa
NUPR1 nuclear protein, transcriptional regulator, 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PHF11 PHD finger protein 11
PMM2 phosphomannomutase 2
PPAN peter pan homolog (Drosophila)
PPCS phosphopantothenoylcysteine synthetase
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PXDC1 PX domain containing 1
PYCARD PYD and CARD domain containing
RBL1 retinoblastoma-like 1
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAF8 SR-related CTD-associated factor 8
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SETMAR SET domain and mariner transposase fusion gene
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMYD5 SMYD family member 5
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
STRN4 striatin, calmodulin binding protein 4
STXBP3 syntaxin binding protein 3
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOR3A torsin family 3, member A
TRIB3 tribbles pseudokinase 3
TTC31 tetratricopeptide repeat domain 31
VEGFC vascular endothelial growth factor C
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR6 WD repeat domain 6
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF165 zinc finger protein 165
ZNF532 zinc finger protein 532
ZNF562 zinc finger protein 562
ZNF787 zinc finger protein 787
ZSCAN31 zinc finger and SCAN domain containing 31
ZZZ3 zinc finger, ZZ-type containing 3