trichostatin A-1732 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-1732 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
AKAP13 A kinase (PRKA) anchor protein 13
AMT aminomethyltransferase
ANKMY2 ankyrin repeat and MYND domain containing 2
APOM apolipoprotein M
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BACE1 beta-site APP-cleaving enzyme 1
BLVRA biliverdin reductase A
C1ORF21 chromosome 1 open reading frame 21
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCSER2 coiled-coil serine-rich protein 2
CD2AP CD2-associated protein
CDK5 cyclin-dependent kinase 5
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEND1 cell cycle exit and neuronal differentiation 1
CEP70 centrosomal protein 70kDa
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CNTNAP1 contactin associated protein 1
CRAT carnitine O-acetyltransferase
CREB3 cAMP responsive element binding protein 3
CRYZ crystallin, zeta (quinone reductase)
DDAH2 dimethylarginine dimethylaminohydrolase 2
DOCK4 dedicator of cytokinesis 4
DOPEY1 dopey family member 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECI2 enoyl-CoA delta isomerase 2
EPAS1 endothelial PAS domain protein 1
EXPH5 exophilin 5
F11R F11 receptor
FAM134B family with sequence similarity 134, member B
FASTK Fas-activated serine/threonine kinase
FGFR1 fibroblast growth factor receptor 1
FSCN3 fascin actin-bundling protein 3, testicular
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GJB1 gap junction protein, beta 1, 32kDa
GJD2 gap junction protein, delta 2, 36kDa
GLRX glutaredoxin (thioltransferase)
GLTP glycolipid transfer protein
GOLM1 golgi membrane protein 1
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HOMER1 homer scaffolding protein 1
HSDL2 hydroxysteroid dehydrogenase like 2
IL11 interleukin 11
INPP5K inositol polyphosphate-5-phosphatase K
INVS inversin
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF5C kinesin family member 5C
KLF6 Kruppel-like factor 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MCC mutated in colorectal cancers
MEF2D myocyte enhancer factor 2D
MIPEP mitochondrial intermediate peptidase
MPZL1 myelin protein zero-like 1
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPDC1 neural proliferation, differentiation and control, 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NSFL1C NSFL1 (p97) cofactor (p47)
NUCB2 nucleobindin 2
NXPH3 neurexophilin 3
NXT2 nuclear transport factor 2-like export factor 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PCYOX1 prenylcysteine oxidase 1
PEX3 peroxisomal biogenesis factor 3
PFN2 profilin 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIAS4 protein inhibitor of activated STAT, 4
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLD2 phospholipase D2
PLS1 plastin 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
QPCT glutaminyl-peptide cyclotransferase
RARA retinoic acid receptor, alpha
RECQL4 RecQ protein-like 4
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SATB1 SATB homeobox 1
SCAF4 SR-related CTD-associated factor 4
SEC31B SEC31 homolog B (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SOD2 superoxide dismutase 2, mitochondrial
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STXBP1 syntaxin binding protein 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF4 transcription factor 4
TLN2 talin 2
TMEM161A transmembrane protein 161A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNS1 tensin 1
TPD52L1 tumor protein D52-like 1
TRIB2 tribbles pseudokinase 2
TUFT1 tuftelin 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WDR19 WD repeat domain 19
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF14 zinc finger protein 14

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANPEP alanyl (membrane) aminopeptidase
ASB13 ankyrin repeat and SOCS box containing 13
AVEN apoptosis, caspase activation inhibitor
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN1 calpain 1, (mu/I) large subunit
CARD9 caspase recruitment domain family, member 9
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CD9 CD9 molecule
CHKB choline kinase beta
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
CNPY3 canopy FGF signaling regulator 3
COA7 cytochrome c oxidase assembly factor 7 (putative)
COMMD10 COMM domain containing 10
CTDNEP1 CTD nuclear envelope phosphatase 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DAZAP1 DAZ associated protein 1
DBF4B DBF4 zinc finger B
DENND4B DENN/MADD domain containing 4B
DOK2 docking protein 2, 56kDa
DOLPP1 dolichyldiphosphatase 1
ENDOG endonuclease G
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM188A family with sequence similarity 188, member A
FAM216A family with sequence similarity 216, member A
FBXW4 F-box and WD repeat domain containing 4
FMNL1 formin-like 1
FPGS folylpolyglutamate synthase
GMIP GEM interacting protein
GPRC5D G protein-coupled receptor, class C, group 5, member D
H2BFS H2B histone family, member S (pseudogene)
HMG20A high mobility group 20A
IFRD2 interferon-related developmental regulator 2
IMMT inner membrane protein, mitochondrial
JUNB jun B proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIAS lipoic acid synthetase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCM5 minichromosome maintenance complex component 5
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MNT MAX network transcriptional repressor
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MRPS34 mitochondrial ribosomal protein S34
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTG1 mitochondrial ribosome-associated GTPase 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUP93 nucleoporin 93kDa
NUPL1 nucleoporin like 1
ORC1 origin recognition complex, subunit 1
ORM1 orosomucoid 1
PARN poly(A)-specific ribonuclease
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PNOC prepronociceptin
POGLUT1 protein O-glucosyltransferase 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRR14L proline rich 14-like
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PUS1 pseudouridylate synthase 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RGS19 regulator of G-protein signaling 19
RPP40 ribonuclease P/MRP 40kDa subunit
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RWDD2B RWD domain containing 2B
SAC3D1 SAC3 domain containing 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC38A10 solute carrier family 38, member 10
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SUN2 Sad1 and UNC84 domain containing 2
THOP1 thimet oligopeptidase 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM214 transmembrane protein 214
TOE1 target of EGR1, member 1 (nuclear)
TROAP trophinin associated protein
TTC27 tetratricopeptide repeat domain 27
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBL4A ubiquitin-like 4A
UBXN8 UBX domain protein 8
UNG uracil-DNA glycosylase
URGCP upregulator of cell proliferation
USP16 ubiquitin specific peptidase 16
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZMPSTE24 zinc metallopeptidase STE24