trichostatin A-1659 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-1659 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
BACE1 beta-site APP-cleaving enzyme 1
BAIAP3 BAI1-associated protein 3
BCL6 B-cell CLL/lymphoma 6
CCDC28A coiled-coil domain containing 28A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP104 centrosomal protein 104kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYB5R1 cytochrome b5 reductase 1
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA2 heat shock 70kDa protein 2
IGFBP3 insulin-like growth factor binding protein 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAKMIP2 janus kinase and microtubule interacting protein 2
KIAA0513 KIAA0513
KIFAP3 kinesin-associated protein 3
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
NEU1 sialidase 1 (lysosomal sialidase)
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
OLFML2A olfactomedin-like 2A
PADI3 peptidyl arginine deiminase, type III
PCDH9 protocadherin 9
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMEL premelanosome protein
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRPH peripherin
REEP1 receptor accessory protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPL3L ribosomal protein L3-like
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17A serine/threonine kinase 17a
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TMSB15A thymosin beta 15a
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AKAP8 A kinase (PRKA) anchor protein 8
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ATAD2B ATPase family, AAA domain containing 2B
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BCL2L2 BCL2-like 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDT1 chromatin licensing and DNA replication factor 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNA1 ephrin-A1
EGR3 early growth response 3
ELF4 E74-like factor 4 (ets domain transcription factor)
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB2 glucocorticoid modulatory element binding protein 2
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
JADE3 jade family PHD finger 3
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MICALL1 MICAL-like 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCOA6 nuclear receptor coactivator 6
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
POGK pogo transposable element with KRAB domain
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SCRN1 secernin 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SNHG20 small nucleolar RNA host gene 20
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TGIF1 TGFB-induced factor homeobox 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNS3 tensin 3
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
USP21 ubiquitin specific peptidase 21
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF32 zinc finger protein 32
ZNF692 zinc finger protein 692