trichostatin A-1637 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-1637 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSF2 acyl-CoA synthetase family member 2
ADM adrenomedullin
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BACE1 beta-site APP-cleaving enzyme 1
BLVRA biliverdin reductase A
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLCE glucuronic acid epimerase
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
H1F0 H1 histone family, member 0
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
MXI1 MAX interactor 1, dimerization protein
NAV2 neuron navigator 2
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK1 NIMA-related kinase 1
NME5 NME/NM23 family member 5
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
OLFML2A olfactomedin-like 2A
OPTN optineurin
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PPARD peroxisome proliferator-activated receptor delta
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRPH peripherin
PTCH1 patched 1
PTRF polymerase I and transcript release factor
RAB40B RAB40B, member RAS oncogene family
REEP1 receptor accessory protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SREBF1 sterol regulatory element binding transcription factor 1
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TBXA2R thromboxane A2 receptor
TRIM2 tripartite motif containing 2
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene
ZNF365 zinc finger protein 365
ZNF45 zinc finger protein 45

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BATF basic leucine zipper transcription factor, ATF-like
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CISH cytokine inducible SH2-containing protein
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCTN4 dynactin 4 (p62)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EGR3 early growth response 3
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT6B K(lysine) acetyltransferase 6B
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LAMA3 laminin, alpha 3
LMNB1 lamin B1
LPAR2 lysophosphatidic acid receptor 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
MPDU1 mannose-P-dolichol utilization defect 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NARFL nuclear prelamin A recognition factor-like
NCSTN nicastrin
NMI N-myc (and STAT) interactor
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
PP14571 uncharacterized LOC100130449
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRNP prion protein
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBL1 retinoblastoma-like 1
RBM23 RNA binding motif protein 23
SCRN1 secernin 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG9 SMG9 nonsense mediated mRNA decay factor
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VRK2 vaccinia related kinase 2
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZBED5 zinc finger, BED-type containing 5
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF552 zinc finger protein 552
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2