trichostatin A-1612 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-1612 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABHD3 abhydrolase domain containing 3
ACP6 acid phosphatase 6, lysophosphatidic
ADD3 adducin 3 (gamma)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP10D ATPase, class V, type 10D
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATR ATR serine/threonine kinase
BAD BCL2-associated agonist of cell death
BIN1 bridging integrator 1
BLVRB biliverdin reductase B
C16ORF58 chromosome 16 open reading frame 58
C19ORF66 chromosome 19 open reading frame 66
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCL20 chemokine (C-C motif) ligand 20
CCSER2 coiled-coil serine-rich protein 2
CD59 CD59 molecule, complement regulatory protein
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEP68 centrosomal protein 68kDa
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CREB3 cAMP responsive element binding protein 3
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYB5A cytochrome b5 type A (microsomal)
DFNA5 deafness, autosomal dominant 5
DHRS1 dehydrogenase/reductase (SDR family) member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECI2 enoyl-CoA delta isomerase 2
ENAH enabled homolog (Drosophila)
EPAS1 endothelial PAS domain protein 1
EXT2 exostosin glycosyltransferase 2
EXTL2 exostosin-like glycosyltransferase 2
F11R F11 receptor
FAM49A family with sequence similarity 49, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1 fibroblast growth factor receptor 1
FUCA1 fucosidase, alpha-L- 1, tissue
GBAP1 glucosidase, beta, acid pseudogene 1
GCA grancalcin, EF-hand calcium binding protein
GGCX gamma-glutamyl carboxylase
GPSM2 G-protein signaling modulator 2
GSTM4 glutathione S-transferase mu 4
IFI16 interferon, gamma-inducible protein 16
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITM2C integral membrane protein 2C
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF5C kinesin family member 5C
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF13 Kruppel-like factor 13
LPAR6 lysophosphatidic acid receptor 6
LTA4H leukotriene A4 hydrolase
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MCAM melanoma cell adhesion molecule
MEF2C myocyte enhancer factor 2C
MEGF9 multiple EGF-like-domains 9
METTL7A methyltransferase like 7A
MINPP1 multiple inositol-polyphosphate phosphatase 1
MOB3B MOB kinase activator 3B
MOSPD2 motile sperm domain containing 2
MPZL1 myelin protein zero-like 1
MTSS1 metastasis suppressor 1
NDE1 nudE neurodevelopment protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NMRK1 nicotinamide riboside kinase 1
PCNXL2 pecanex-like 2 (Drosophila)
PCSK7 proprotein convertase subtilisin/kexin type 7
PFN2 profilin 2
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G12A phospholipase A2, group XIIA
PLS1 plastin 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTX3 pentraxin 3, long
RAB28 RAB28, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RARS arginyl-tRNA synthetase
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RIOK3 RIO kinase 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
SAR1B secretion associated, Ras related GTPase 1B
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOAT1 sterol O-acyltransferase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
TPD52L1 tumor protein D52-like 1
TPR translocated promoter region, nuclear basket protein
TRIB2 tribbles pseudokinase 2
TSPAN13 tetraspanin 13
TUFT1 tuftelin 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZFYVE16 zinc finger, FYVE domain containing 16

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACSL5 acyl-CoA synthetase long-chain family member 5
ADI1 acireductone dioxygenase 1
AVEN apoptosis, caspase activation inhibitor
C10ORF2 chromosome 10 open reading frame 2
C17ORF70 chromosome 17 open reading frame 70
C1ORF174 chromosome 1 open reading frame 174
C9ORF40 chromosome 9 open reading frame 40
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CARD9 caspase recruitment domain family, member 9
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC9 coiled-coil domain containing 9
CD151 CD151 molecule (Raph blood group)
CIC capicua transcriptional repressor
COMMD10 COMM domain containing 10
CTSG cathepsin G
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DPP3 dipeptidyl-peptidase 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
E2F6 E2F transcription factor 6
FAM136A family with sequence similarity 136, member A
FAM216A family with sequence similarity 216, member A
FAM222B family with sequence similarity 222, member B
FGR FGR proto-oncogene, Src family tyrosine kinase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GMIP GEM interacting protein
GRAMD4 GRAM domain containing 4
GTPBP3 GTP binding protein 3 (mitochondrial)
GTPBP6 GTP binding protein 6 (putative)
HINFP histone H4 transcription factor
HMHA1 histocompatibility (minor) HA-1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFRD2 interferon-related developmental regulator 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCTD15 potassium channel tetramerization domain containing 15
KLHL21 kelch-like family member 21
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMNB1 lamin B1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAT2A methionine adenosyltransferase II, alpha
MATK megakaryocyte-associated tyrosine kinase
MEPCE methylphosphate capping enzyme
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MON1B MON1 secretory trafficking family member B
MRPL12 mitochondrial ribosomal protein L12
MRPS34 mitochondrial ribosomal protein S34
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
MYO9A myosin IXA
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAGR1 PAXIP1 associated glutamate-rich protein 1
PEF1 penta-EF-hand domain containing 1
PES1 pescadillo ribosomal biogenesis factor 1
PFAS phosphoribosylformylglycinamidine synthase
PHF21A PHD finger protein 21A
PRMT3 protein arginine methyltransferase 3
PRTN3 proteinase 3
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCO2 SCO2 cytochrome c oxidase assembly protein
SDCCAG3 serologically defined colon cancer antigen 3
SEH1L SEH1-like (S. cerevisiae)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SNHG3 small nucleolar RNA host gene 3
SNUPN snurportin 1
SPI1 Spi-1 proto-oncogene
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STAG1 stromal antigen 1
STEAP3 STEAP family member 3, metalloreductase
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TFB2M transcription factor B2, mitochondrial
THOC6 THO complex 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TIPIN TIMELESS interacting protein
TMEM11 transmembrane protein 11
TSPAN14 tetraspanin 14
TTC27 tetratricopeptide repeat domain 27
TTK TTK protein kinase
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UCK2 uridine-cytidine kinase 2
UNG uracil-DNA glycosylase
XPOT exportin, tRNA
ZCCHC8 zinc finger, CCHC domain containing 8
ZEB2 zinc finger E-box binding homeobox 2
ZNF16 zinc finger protein 16
ZNF692 zinc finger protein 692
ZNF804A zinc finger protein 804A