trichostatin A-1400 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-1400 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADD3 adducin 3 (gamma)
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASMTL acetylserotonin O-methyltransferase-like
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C5ORF45 chromosome 5 open reading frame 45
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCPG1 cell cycle progression 1
CD59 CD59 molecule, complement regulatory protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CKB creatine kinase, brain
CLCN6 chloride channel, voltage-sensitive 6
CLEC2B C-type lectin domain family 2, member B
CPNE3 copine III
CRAT carnitine O-acetyltransferase
CREB3 cAMP responsive element binding protein 3
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAAM1 dishevelled associated activator of morphogenesis 1
DFNA5 deafness, autosomal dominant 5
DHRS1 dehydrogenase/reductase (SDR family) member 1
DTX4 deltex 4, E3 ubiquitin ligase
DYNLT3 dynein, light chain, Tctex-type 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECI2 enoyl-CoA delta isomerase 2
EPAS1 endothelial PAS domain protein 1
EXTL2 exostosin-like glycosyltransferase 2
F11R F11 receptor
FAM134B family with sequence similarity 134, member B
FAM63A family with sequence similarity 63, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1 fibroblast growth factor receptor 1
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GIMAP5 GTPase, IMAP family member 5
GNS glucosamine (N-acetyl)-6-sulfatase
HEG1 heart development protein with EGF-like domains 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IFI16 interferon, gamma-inducible protein 16
IL1RAP interleukin 1 receptor accessory protein
JRKL JRK-like
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF5C kinesin family member 5C
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LZTFL1 leucine zipper transcription factor-like 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK4 MAP/microtubule affinity-regulating kinase 4
MCAM melanoma cell adhesion molecule
MPZL1 myelin protein zero-like 1
MTSS1 metastasis suppressor 1
NEU1 sialidase 1 (lysosomal sialidase)
NME7 NME/NM23 family member 7
NMRK1 nicotinamide riboside kinase 1
ORC4 origin recognition complex, subunit 4
PAQR6 progestin and adipoQ receptor family member VI
PARG poly (ADP-ribose) glycohydrolase
PCGF2 polycomb group ring finger 2
PEX3 peroxisomal biogenesis factor 3
PIDD1 p53-induced death domain protein 1
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PLA2G12A phospholipase A2, group XIIA
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCD1 phospholipase C, delta 1
PLS1 plastin 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTX3 pentraxin 3, long
RECQL RecQ helicase-like
RHOC ras homolog family member C
SATB1 SATB homeobox 1
SCAPER S-phase cyclin A-associated protein in the ER
SECISBP2L SECIS binding protein 2-like
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFTPB surfactant protein B
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SOAT1 sterol O-acyltransferase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK38L serine/threonine kinase 38 like
STX17 syntaxin 17
STXBP1 syntaxin binding protein 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TMEM45A transmembrane protein 45A
TPD52L1 tumor protein D52-like 1
TPT1 tumor protein, translationally-controlled 1
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TUFT1 tuftelin 1
UBL3 ubiquitin-like 3
WASF1 WAS protein family, member 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACIN1 apoptotic chromatin condensation inducer 1
ADI1 acireductone dioxygenase 1
ANKRD40 ankyrin repeat domain 40
AVEN apoptosis, caspase activation inhibitor
C10ORF2 chromosome 10 open reading frame 2
C3AR1 complement component 3a receptor 1
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CTPS1 CTP synthase 1
CYC1 cytochrome c-1
DCPS decapping enzyme, scavenger
DPP3 dipeptidyl-peptidase 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENDOG endonuclease G
EXOC3 exocyst complex component 3
FAM136A family with sequence similarity 136, member A
FAM216A family with sequence similarity 216, member A
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
FXN frataxin
GMIP GEM interacting protein
GMPPB GDP-mannose pyrophosphorylase B
GRWD1 glutamate-rich WD repeat containing 1
GSE1 Gse1 coiled-coil protein
GTPBP6 GTP binding protein 6 (putative)
HIST1H2BK histone cluster 1, H2bk
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMHA1 histocompatibility (minor) HA-1
IFITM3 interferon induced transmembrane protein 3
IFRD2 interferon-related developmental regulator 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KLHL21 kelch-like family member 21
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LTB lymphotoxin beta (TNF superfamily, member 3)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK12 mitogen-activated protein kinase 12
MATK megakaryocyte-associated tyrosine kinase
MFSD11 major facilitator superfamily domain containing 11
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPDU1 mannose-P-dolichol utilization defect 1
MRPS34 mitochondrial ribosomal protein S34
MTG1 mitochondrial ribosome-associated GTPase 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NCSTN nicastrin
NEFH neurofilament, heavy polypeptide
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAK1IP1 PAK1 interacting protein 1
PEF1 penta-EF-hand domain containing 1
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PUS1 pseudouridylate synthase 1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBMS3 RNA binding motif, single stranded interacting protein 3
RIN1 Ras and Rab interactor 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCO2 SCO2 cytochrome c oxidase assembly protein
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNX17 sorting nexin 17
SPI1 Spi-1 proto-oncogene
SPON2 spondin 2, extracellular matrix protein
STEAP3 STEAP family member 3, metalloreductase
TERT telomerase reverse transcriptase
THOC6 THO complex 6
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBIAD1 UbiA prenyltransferase domain containing 1
UBL4A ubiquitin-like 4A
UCK2 uridine-cytidine kinase 2
URGCP upregulator of cell proliferation
USP16 ubiquitin specific peptidase 16
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VSIG4 V-set and immunoglobulin domain containing 4
XAF1 XIAP associated factor 1
ZBED1 zinc finger, BED-type containing 1
ZNF408 zinc finger protein 408