trichostatin A-1306 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-1306 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD6 abhydrolase domain containing 6
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACP6 acid phosphatase 6, lysophosphatidic
ADAM23 ADAM metallopeptidase domain 23
ADAM28 ADAM metallopeptidase domain 28
ADGRL1 adhesion G protein-coupled receptor L1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL3 ADP-ribosylation factor-like 3
ARL4C ADP-ribosylation factor-like 4C
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP10D ATPase, class V, type 10D
ATP13A2 ATPase type 13A2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BACE1 beta-site APP-cleaving enzyme 1
BIK BCL2-interacting killer (apoptosis-inducing)
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD48 CD48 molecule
CD59 CD59 molecule, complement regulatory protein
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP70 centrosomal protein 70kDa
CLGN calmegin
CPM carboxypeptidase M
CPNE3 copine III
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYB5R1 cytochrome b5 reductase 1
DHRS1 dehydrogenase/reductase (SDR family) member 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM3 dynamin 3
DOCK4 dedicator of cytokinesis 4
DSE dermatan sulfate epimerase
ECI2 enoyl-CoA delta isomerase 2
EPAS1 endothelial PAS domain protein 1
EXTL2 exostosin-like glycosyltransferase 2
F11R F11 receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXD1 forkhead box D1
FUCA1 fucosidase, alpha-L- 1, tissue
GCAT glycine C-acetyltransferase
GCH1 GTP cyclohydrolase 1
GIPC1 GIPC PDZ domain containing family, member 1
GLRX glutaredoxin (thioltransferase)
GLTP glycolipid transfer protein
GM2A GM2 ganglioside activator
GPR65 G protein-coupled receptor 65
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HOXA1 homeobox A1
HOXA5 homeobox A5
HRH1 histamine receptor H1
HRSP12 heat-responsive protein 12
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF5C kinesin family member 5C
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MED27 mediator complex subunit 27
MPZL1 myelin protein zero-like 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH10 myosin, heavy chain 10, non-muscle
NCAM1 neural cell adhesion molecule 1
NMRK1 nicotinamide riboside kinase 1
PADI2 peptidyl arginine deiminase, type II
PCNXL2 pecanex-like 2 (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PEX1 peroxisomal biogenesis factor 1
PEX6 peroxisomal biogenesis factor 6
PFKM phosphofructokinase, muscle
PFN2 profilin 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RRAS related RAS viral (r-ras) oncogene homolog
SRR serine racemase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
THAP10 THAP domain containing 10
TPD52L1 tumor protein D52-like 1
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
ZBTB20 zinc finger and BTB domain containing 20
ZNF609 zinc finger protein 609
ZSCAN16 zinc finger and SCAN domain containing 16

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP1 ArfGAP with dual PH domains 1
ADI1 acireductone dioxygenase 1
AES amino-terminal enhancer of split
ANKRD40 ankyrin repeat domain 40
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARMC6 armadillo repeat containing 6
BRIX1 BRX1, biogenesis of ribosomes
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCL2 chemokine (C-C motif) ligand 2
CDK3 cyclin-dependent kinase 3
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CECR1 cat eye syndrome chromosome region, candidate 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLTCL1 clathrin, heavy chain-like 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DENND4B DENN/MADD domain containing 4B
DGAT1 diacylglycerol O-acyltransferase 1
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DPH2 DPH2 homolog (S. cerevisiae)
ECHDC2 enoyl CoA hydratase domain containing 2
ECSIT ECSIT signalling integrator
FAM86B1 family with sequence similarity 86, member B1
FAR2 fatty acyl CoA reductase 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FXN frataxin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GFI1 growth factor independent 1 transcription repressor
GMIP GEM interacting protein
GTF2I general transcription factor IIi
GTPBP6 GTP binding protein 6 (putative)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
IFRD2 interferon-related developmental regulator 2
ISG15 ISG15 ubiquitin-like modifier
KCTD15 potassium channel tetramerization domain containing 15
KLHDC4 kelch domain containing 4
KRI1 KRI1 homolog (S. cerevisiae)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIMD2 LIM domain containing 2
LMNB1 lamin B1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MBTD1 mbt domain containing 1
MCRS1 microspherule protein 1
MEPCE methylphosphate capping enzyme
METTL2B methyltransferase like 2B
MILR1 mast cell immunoglobulin-like receptor 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MON1B MON1 secretory trafficking family member B
MPDU1 mannose-P-dolichol utilization defect 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOL6 nucleolar protein 6 (RNA-associated)
NSD1 nuclear receptor binding SET domain protein 1
NT5C 5', 3'-nucleotidase, cytosolic
PEX26 peroxisomal biogenesis factor 26
PISD phosphatidylserine decarboxylase
PMF1 polyamine-modulated factor 1
PNOC prepronociceptin
PPAN peter pan homolog (Drosophila)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RABL3 RAB, member of RAS oncogene family-like 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RNH1 ribonuclease/angiogenin inhibitor 1
RPAP1 RNA polymerase II associated protein 1
RPP40 ribonuclease P/MRP 40kDa subunit
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
S100A12 S100 calcium binding protein A12
SCO2 SCO2 cytochrome c oxidase assembly protein
SETD1B SET domain containing 1B
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNHG20 small nucleolar RNA host gene 20
SNUPN snurportin 1
SPI1 Spi-1 proto-oncogene
TERT telomerase reverse transcriptase
TMEM39B transmembrane protein 39B
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN32 tetraspanin 32
UBQLN4 ubiquilin 4
UNG uracil-DNA glycosylase
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR5B WD repeat domain 5B
XAF1 XIAP associated factor 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF32 zinc finger protein 32