trichostatin A-1284 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-1284 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD12 ankyrin repeat domain 12
ANKRD6 ankyrin repeat domain 6
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL4C ADP-ribosylation factor-like 4C
ARMC7 armadillo repeat containing 7
ATP10D ATPase, class V, type 10D
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BIN1 bridging integrator 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNT2 cyclin T2
CD59 CD59 molecule, complement regulatory protein
CEP70 centrosomal protein 70kDa
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DHRS1 dehydrogenase/reductase (SDR family) member 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DSE dermatan sulfate epimerase
DZIP3 DAZ interacting zinc finger protein 3
ECI2 enoyl-CoA delta isomerase 2
ENAH enabled homolog (Drosophila)
EXPH5 exophilin 5
F11R F11 receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1 fibroblast growth factor receptor 1
FIG4 FIG4 phosphoinositide 5-phosphatase
FST follistatin
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GIPC1 GIPC PDZ domain containing family, member 1
GLG1 golgi glycoprotein 1
GLRX glutaredoxin (thioltransferase)
GPR65 G protein-coupled receptor 65
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXA1 homeobox A1
HSPA4 heat shock 70kDa protein 4
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP4 microtubule-associated protein 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MEF2C myocyte enhancer factor 2C
METTL7A methyltransferase like 7A
MKL2 MKL/myocardin-like 2
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MPZL1 myelin protein zero-like 1
MREG melanoregulin
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCAM1 neural cell adhesion molecule 1
NMRK1 nicotinamide riboside kinase 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PALLD palladin, cytoskeletal associated protein
PCGF2 polycomb group ring finger 2
PDE4DIP phosphodiesterase 4D interacting protein
PFDN6 prefoldin subunit 6
PFKM phosphofructokinase, muscle
PFN2 profilin 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
PMP22 peripheral myelin protein 22
POU4F1 POU class 4 homeobox 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
SAMD4A sterile alpha motif domain containing 4A
SATB1 SATB homeobox 1
SEC24A SEC24 family member A
SGCE sarcoglycan, epsilon
SIDT1 SID1 transmembrane family, member 1
SLAMF7 SLAM family member 7
SLITRK5 SLIT and NTRK-like family, member 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
SV2A synaptic vesicle glycoprotein 2A
TCF4 transcription factor 4
TCTN1 tectonic family member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM134 transmembrane protein 134
TPD52L1 tumor protein D52-like 1
TRAM2 translocation associated membrane protein 2
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TSPAN5 tetraspanin 5
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
ZNF529 zinc finger protein 529

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AGO4 argonaute RISC catalytic component 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOBR apolipoprotein B receptor
APOL6 apolipoprotein L, 6
ARID5A AT rich interactive domain 5A (MRF1-like)
AVEN apoptosis, caspase activation inhibitor
BAHCC1 BAH domain and coiled-coil containing 1
BRMS1 breast cancer metastasis suppressor 1
BTBD18 BTB (POZ) domain containing 18
C14ORF159 chromosome 14 open reading frame 159
C5AR1 complement component 5a receptor 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN15 calpain 15
CASD1 CAS1 domain containing 1
CCDC94 coiled-coil domain containing 94
CCL2 chemokine (C-C motif) ligand 2
CD38 CD38 molecule
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPTP ceramide-1-phosphate transfer protein
CYB561D2 cytochrome b561 family, member D2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCPS decapping enzyme, scavenger
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND2D DENN/MADD domain containing 2D
DEPTOR DEP domain containing MTOR-interacting protein
DPP3 dipeptidyl-peptidase 3
ECHDC2 enoyl CoA hydratase domain containing 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR3 early growth response 3
ERCC2 excision repair cross-complementation group 2
FAR2 fatty acyl CoA reductase 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FHIT fragile histidine triad
FKBP9 FK506 binding protein 9, 63 kDa
GAMT guanidinoacetate N-methyltransferase
GRAMD1B GRAM domain containing 1B
GSTZ1 glutathione S-transferase zeta 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFRD2 interferon-related developmental regulator 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF7 interferon regulatory factor 7
KAT2A K(lysine) acetyltransferase 2A
KPTN kaptin (actin binding protein)
KRI1 KRI1 homolog (S. cerevisiae)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIMD2 LIM domain containing 2
LRRK1 leucine-rich repeat kinase 1
LY6E lymphocyte antigen 6 complex, locus E
MAGEF1 melanoma antigen family F1
MCM9 minichromosome maintenance complex component 9
MCRS1 microspherule protein 1
MED9 mediator complex subunit 9
METTL8 methyltransferase like 8
MICALL2 MICAL-like 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO19 myosin XIX
N4BP2L2-IT2 N4BPL2 intronic transcript 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCNT pericentrin
PCOLCE2 procollagen C-endopeptidase enhancer 2
PMF1 polyamine-modulated factor 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS19 regulator of G-protein signaling 19
RHOH ras homolog family member H
RPP38 ribonuclease P/MRP 38kDa subunit
RRP1 ribosomal RNA processing 1
RWDD3 RWD domain containing 3
S1PR4 sphingosine-1-phosphate receptor 4
SLC10A3 solute carrier family 10, member 3
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMYD5 SMYD family member 5
SPI1 Spi-1 proto-oncogene
SPON2 spondin 2, extracellular matrix protein
STBD1 starch binding domain 1
TBC1D17 TBC1 domain family, member 17
TERT telomerase reverse transcriptase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM164 transmembrane protein 164
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTC27 tetratricopeptide repeat domain 27
TUBA3C tubulin, alpha 3c
UNG uracil-DNA glycosylase
USP36 ubiquitin specific peptidase 36
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VILL villin-like
WBSCR16 Williams-Beuren syndrome chromosome region 16
WNT10B wingless-type MMTV integration site family, member 10B
ZNF350 zinc finger protein 350
ZSCAN5A zinc finger and SCAN domain containing 5A