trichostatin A-1212 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-1212 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AHNAK2 AHNAK nucleoprotein 2
AQP3 aquaporin 3 (Gill blood group)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVPI1 arginine vasopressin-induced 1
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
CA5B carbonic anhydrase VB, mitochondrial
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CFAP69 cilia and flagella associated protein 69
CHN2 chimerin 2
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
EFNB2 ephrin-B2
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
EPHA4 EPH receptor A4
EPHB3 EPH receptor B3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FLRT3 fibronectin leucine rich transmembrane protein 3
FYN FYN proto-oncogene, Src family tyrosine kinase
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1FX H1 histone family, member X
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ING1 inhibitor of growth family, member 1
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
ISL1 ISL LIM homeobox 1
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPIN1 lipin 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAP2K3 mitogen-activated protein kinase kinase 3
MERTK MER proto-oncogene, tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDH9 protocadherin 9
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLK2 polo-like kinase 2
PTCH1 patched 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RNF24 ring finger protein 24
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SORBS1 sorbin and SH3 domain containing 1
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
SYBU syntabulin (syntaxin-interacting)
SYT1 synaptotagmin I
TBC1D2 TBC1 domain family, member 2
TBPL1 TBP-like 1
TGFBR3 transforming growth factor, beta receptor III
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
ZNF277 zinc finger protein 277

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATF1 activating transcription factor 1
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BCAS3 breast carcinoma amplified sequence 3
BCL7A B-cell CLL/lymphoma 7A
BMP2 bone morphogenetic protein 2
BOLA1 bolA family member 1
BRD9 bromodomain containing 9
C19ORF40 chromosome 19 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBR3 carbonyl reductase 3
CCDC51 coiled-coil domain containing 51
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
COIL coilin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSNK1D casein kinase 1, delta
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
DMBT1 deleted in malignant brain tumors 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOCK1 dedicator of cytokinesis 1
FST follistatin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBX2 gastrulation brain homeobox 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2I general transcription factor IIi
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
HSPB8 heat shock 22kDa protein 8
IL33 interleukin 33
IL7R interleukin 7 receptor
IMPACT impact RWD domain protein
INHBB inhibin, beta B
KAT5 K(lysine) acetyltransferase 5
KAT6B K(lysine) acetyltransferase 6B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LIF leukemia inhibitory factor
LMNB1 lamin B1
LOXL1 lysyl oxidase-like 1
MCRS1 microspherule protein 1
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MFSD6 major facilitator superfamily domain containing 6
NMI N-myc (and STAT) interactor
NNMT nicotinamide N-methyltransferase
NUPR1 nuclear protein, transcriptional regulator, 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARP2 poly (ADP-ribose) polymerase 2
PEF1 penta-EF-hand domain containing 1
PLK1 polo-like kinase 1
PPAP2B phosphatidic acid phosphatase type 2B
QRICH1 glutamine-rich 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM23 RNA binding motif protein 23
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RPL13P5 ribosomal protein L13 pseudogene 5
RSAD1 radical S-adenosyl methionine domain containing 1
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETMAR SET domain and mariner transposase fusion gene
SH2D4A SH2 domain containing 4A
SLC10A3 solute carrier family 10, member 3
SLC12A8 solute carrier family 12, member 8
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TARBP2 TAR (HIV-1) RNA binding protein 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM39B transmembrane protein 39B
TRIB3 tribbles pseudokinase 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZBTB38 zinc finger and BTB domain containing 38
ZC3H7A zinc finger CCCH-type containing 7A
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF112 zinc finger protein 112
ZNF16 zinc finger protein 16
ZNF165 zinc finger protein 165
ZNF280D zinc finger protein 280D
ZNF32 zinc finger protein 32
ZNF532 zinc finger protein 532
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZZZ3 zinc finger, ZZ-type containing 3