trichostatin A-1175 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-1175 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC9 armadillo repeat containing 9
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BIK BCL2-interacting killer (apoptosis-inducing)
BLVRA biliverdin reductase A
C18ORF8 chromosome 18 open reading frame 8
C19ORF66 chromosome 19 open reading frame 66
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCS copper chaperone for superoxide dismutase
CCSER2 coiled-coil serine-rich protein 2
CD59 CD59 molecule, complement regulatory protein
CDKL3 cyclin-dependent kinase-like 3
CEP68 centrosomal protein 68kDa
CGRRF1 cell growth regulator with ring finger domain 1
CPNE3 copine III
CREB3 cAMP responsive element binding protein 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY2 cryptochrome circadian clock 2
CSRNP2 cysteine-serine-rich nuclear protein 2
CTNS cystinosin, lysosomal cystine transporter
CXADR coxsackie virus and adenovirus receptor
CYB5R1 cytochrome b5 reductase 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DNAAF1 dynein, axonemal, assembly factor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK4 dedicator of cytokinesis 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECI2 enoyl-CoA delta isomerase 2
EFNA4 ephrin-A4
EFNB2 ephrin-B2
EPAS1 endothelial PAS domain protein 1
F11R F11 receptor
FAM49A family with sequence similarity 49, member A
FNBP1L formin binding protein 1-like
FUCA1 fucosidase, alpha-L- 1, tissue
GAS2L1 growth arrest-specific 2 like 1
GCDH glutaryl-CoA dehydrogenase
GIPC1 GIPC PDZ domain containing family, member 1
GLRX glutaredoxin (thioltransferase)
GM2A GM2 ganglioside activator
H1F0 H1 histone family, member 0
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
INA internexin neuronal intermediate filament protein, alpha
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
MAK male germ cell-associated kinase
MAP2K6 mitogen-activated protein kinase kinase 6
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MCOLN1 mucolipin 1
MLF1 myeloid leukemia factor 1
MPZL1 myelin protein zero-like 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEU1 sialidase 1 (lysosomal sialidase)
NMRK1 nicotinamide riboside kinase 1
PADI2 peptidyl arginine deiminase, type II
PALLD palladin, cytoskeletal associated protein
PCYOX1 prenylcysteine oxidase 1
PDE4DIP phosphodiesterase 4D interacting protein
PLS1 plastin 1
POLB polymerase (DNA directed), beta
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POR P450 (cytochrome) oxidoreductase
POU4F1 POU class 4 homeobox 1
RAB40B RAB40B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNF25 ring finger protein 25
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRAS related RAS viral (r-ras) oncogene homolog
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
TESK2 testis-specific kinase 2
TPMT thiopurine S-methyltransferase
TSPAN13 tetraspanin 13
TTC26 tetratricopeptide repeat domain 26
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
ZC2HC1A zinc finger, C2HC-type containing 1A
ZSCAN16 zinc finger and SCAN domain containing 16

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ATP8B4 ATPase, class I, type 8B, member 4
BAG2 BCL2-associated athanogene 2
BCOR BCL6 corepressor
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD14 CD14 molecule
CD69 CD69 molecule
CDT1 chromatin licensing and DNA replication factor 1
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CLEC5A C-type lectin domain family 5, member A
CLEC7A C-type lectin domain family 7, member A
CTCF CCCTC-binding factor (zinc finger protein)
CTPS1 CTP synthase 1
CUL1 cullin 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYTIP cytohesin 1 interacting protein
DENND4B DENN/MADD domain containing 4B
EVI2B ecotropic viral integration site 2B
FAM216A family with sequence similarity 216, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
FXN frataxin
GFI1 growth factor independent 1 transcription repressor
GPR18 G protein-coupled receptor 18
GPR183 G protein-coupled receptor 183
HMHA1 histocompatibility (minor) HA-1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
JADE1 jade family PHD finger 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LMNB1 lamin B1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100129361
LRMP lymphoid-restricted membrane protein
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MEIS2 Meis homeobox 2
MEPCE methylphosphate capping enzyme
MID1IP1 MID1 interacting protein 1
MPDU1 mannose-P-dolichol utilization defect 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSL1 male-specific lethal 1 homolog (Drosophila)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2 nuclear factor, erythroid 2
NMI N-myc (and STAT) interactor
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARP4 poly (ADP-ribose) polymerase family, member 4
PARP8 poly (ADP-ribose) polymerase family, member 8
PECAM1 platelet/endothelial cell adhesion molecule 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PON2 paraoxonase 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTER phosphotriesterase related
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SETD1B SET domain containing 1B
SLA Src-like-adaptor
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG3 small nucleolar RNA host gene 3
SPRY2 sprouty homolog 2 (Drosophila)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
TARP TCR gamma alternate reading frame protein
TGIF1 TGFB-induced factor homeobox 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNIP1 TNFAIP3 interacting protein 1
TRAC T cell receptor alpha constant
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TRIM22 tripartite motif containing 22
TRIM8 tripartite motif containing 8
TXNDC15 thioredoxin domain containing 15
UBXN8 UBX domain protein 8
WT1 Wilms tumor 1
WT1-AS WT1 antisense RNA
XBP1 X-box binding protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZEB2 zinc finger E-box binding homeobox 2
ZNF350 zinc finger protein 350
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692