trichostatin A-1112 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-1112 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ARL4C ADP-ribosylation factor-like 4C
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BACE1 beta-site APP-cleaving enzyme 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C14ORF132 chromosome 14 open reading frame 132
CALCOCO1 calcium binding and coiled-coil domain 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC28A coiled-coil domain containing 28A
CHKA choline kinase alpha
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EAF2 ELL associated factor 2
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPHB3 EPH receptor B3
ETHE1 ethylmalonic encephalopathy 1
EXT1 exostosin glycosyltransferase 1
EXTL2 exostosin-like glycosyltransferase 2
FA2H fatty acid 2-hydroxylase
FN1 fibronectin 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
HSPB11 heat shock protein family B (small), member 11
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
KDM4B lysine (K)-specific demethylase 4B
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
KLHDC10 kelch domain containing 10
KLHL24 kelch-like family member 24
LIMA1 LIM domain and actin binding 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MBNL2 muscleblind-like splicing regulator 2
MLXIP MLX interacting protein
MMD monocyte to macrophage differentiation-associated
MOSPD2 motile sperm domain containing 2
MT2A metallothionein 2A
MXI1 MAX interactor 1, dimerization protein
NEK1 NIMA-related kinase 1
NEU1 sialidase 1 (lysosomal sialidase)
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
OPTN optineurin
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PPARD peroxisome proliferator-activated receptor delta
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRPH peripherin
RAB29 RAB29, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIMS3 regulating synaptic membrane exocytosis 3
RIPK4 receptor-interacting serine-threonine kinase 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFXN3 sideroflexin 3
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SIKE1 suppressor of IKBKE 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SNN stannin
SREBF1 sterol regulatory element binding transcription factor 1
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17A serine/threonine kinase 17a
STX2 syntaxin 2
STXBP1 syntaxin binding protein 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAOK3 TAO kinase 3
TRIM2 tripartite motif containing 2
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
VCL vinculin
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATF1 activating transcription factor 1
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C7ORF49 chromosome 7 open reading frame 49
C9ORF3 chromosome 9 open reading frame 3
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTPS1 CTP synthase 1
CUL1 cullin 1
CXCL12 chemokine (C-X-C motif) ligand 12
DENND4B DENN/MADD domain containing 4B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DTWD1 DTW domain containing 1
EGR3 early growth response 3
ERBB2IP erbb2 interacting protein
ERF Ets2 repressor factor
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HIRIP3 HIRA interacting protein 3
INHBB inhibin, beta B
INPPL1 inositol polyphosphate phosphatase-like 1
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KEAP1 kelch-like ECH-associated protein 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMNB1 lamin B1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MCRS1 microspherule protein 1
MEPCE methylphosphate capping enzyme
MEX3C mex-3 RNA binding family member C
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA6 nuclear receptor coactivator 6
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUP62 nucleoporin 62kDa
PAPD7 PAP associated domain containing 7
POGK pogo transposable element with KRAB domain
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPAN peter pan homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR15L proline rich 15-like
PUS1 pseudouridylate synthase 1
QRICH1 glutamine-rich 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RBM39 RNA binding motif protein 39
RBM4B RNA binding motif protein 4B
RNF44 ring finger protein 44
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAF8 SR-related CTD-associated factor 8
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCERG1 transcription elongation regulator 1
TMEM30B transmembrane protein 30B
TOE1 target of EGR1, member 1 (nuclear)
TOR3A torsin family 3, member A
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSKU tsukushi, small leucine rich proteoglycan
UBXN8 UBX domain protein 8
UNKL unkempt family zinc finger-like
USP21 ubiquitin specific peptidase 21
VRK2 vaccinia related kinase 2
WDR6 WD repeat domain 6
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZZZ3 zinc finger, ZZ-type containing 3