trichostatin A-1072 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-1072 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
ALAS1 5'-aminolevulinate synthase 1
ALDOC aldolase C, fructose-bisphosphate
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C2ORF44 chromosome 2 open reading frame 44
CALCOCO1 calcium binding and coiled-coil domain 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHKA choline kinase alpha
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EHD1 EH-domain containing 1
ELOVL4 ELOVL fatty acid elongase 4
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
KIAA0513 KIAA0513
KLHL26 kelch-like family member 26
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MT1F metallothionein 1F
MXI1 MAX interactor 1, dimerization protein
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK1 NIMA-related kinase 1
NEU1 sialidase 1 (lysosomal sialidase)
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OASL 2'-5'-oligoadenylate synthetase-like
OPTN optineurin
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDH9 protocadherin 9
PCYOX1L prenylcysteine oxidase 1 like
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
RAB40B RAB40B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RIPK4 receptor-interacting serine-threonine kinase 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SNN stannin
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STK17A serine/threonine kinase 17a
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRIM52 tripartite motif containing 52
TSPAN5 tetraspanin 5
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ATF1 activating transcription factor 1
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CCNJ cyclin J
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
E2F8 E2F transcription factor 8
EFNA1 ephrin-A1
EGR3 early growth response 3
ERBB2IP erbb2 interacting protein
FAM57A family with sequence similarity 57, member A
FAM60A family with sequence similarity 60, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB2 glucocorticoid modulatory element binding protein 2
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KEAP1 kelch-like ECH-associated protein 1
KIAA0753 KIAA0753
KIF15 kinesin family member 15
LMNB1 lamin B1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L2 LUC7-like 2 (S. cerevisiae)
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MEX3C mex-3 RNA binding family member C
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCOA6 nuclear receptor coactivator 6
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUP62 nucleoporin 62kDa
PAPD7 PAP associated domain containing 7
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RBM39 RNA binding motif protein 39
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SLC35F2 solute carrier family 35, member F2
SMAD7 SMAD family member 7
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC2 stanniocalcin 2
TGIF1 TGFB-induced factor homeobox 1
TMEM223 transmembrane protein 223
TMEM30B transmembrane protein 30B
TNS3 tensin 3
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UNKL unkempt family zinc finger-like
WDR43 WD repeat domain 43
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF33B zinc finger protein 33B
ZNF562 zinc finger protein 562
ZNF692 zinc finger protein 692
ZZZ3 zinc finger, ZZ-type containing 3