trichostatin A-1050 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-1050 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
ALAS1 5'-aminolevulinate synthase 1
ALDOC aldolase C, fructose-bisphosphate
BCL6 B-cell CLL/lymphoma 6
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTN2A2 butyrophilin, subfamily 2, member A2
C16ORF45 chromosome 16 open reading frame 45
CALCOCO1 calcium binding and coiled-coil domain 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CYB5R1 cytochrome b5 reductase 1
CYLD cylindromatosis (turban tumor syndrome)
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPAS1 endothelial PAS domain protein 1
EXTL2 exostosin-like glycosyltransferase 2
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
INSIG1 insulin induced gene 1
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
MAP1B microtubule-associated protein 1B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MBNL2 muscleblind-like splicing regulator 2
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MT2A metallothionein 2A
MXI1 MAX interactor 1, dimerization protein
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK1 NIMA-related kinase 1
NEU1 sialidase 1 (lysosomal sialidase)
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OPTN optineurin
PCYOX1L prenylcysteine oxidase 1 like
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PPARD peroxisome proliferator-activated receptor delta
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRPH peripherin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB8B RAB8B, member RAS oncogene family
REEP1 receptor accessory protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFXN3 sideroflexin 3
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC31A2 solute carrier family 31 (copper transporter), member 2
SNN stannin
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX2 syntaxin 2
STXBP1 syntaxin binding protein 1
TAOK3 TAO kinase 3
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRIM2 tripartite motif containing 2
TSPAN5 tetraspanin 5
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UBE2H ubiquitin-conjugating enzyme E2H
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BMPR1A bone morphogenetic protein receptor, type IA
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDT1 chromatin licensing and DNA replication factor 1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
CXCL12 chemokine (C-X-C motif) ligand 12
DENND4B DENN/MADD domain containing 4B
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNA1 ephrin-A1
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FBXW4 F-box and WD repeat domain containing 4
FJX1 four jointed box 1 (Drosophila)
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB2 glucocorticoid modulatory element binding protein 2
GTF2I general transcription factor IIi
HIRIP3 HIRA interacting protein 3
HMGXB4 HMG box domain containing 4
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LAMA5 laminin, alpha 5
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMNB1 lamin B1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LUC7L2 LUC7-like 2 (S. cerevisiae)
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCOA6 nuclear receptor coactivator 6
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGS19 regulator of G-protein signaling 19
RIPPLY3 ripply transcriptional repressor 3
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SLC35F2 solute carrier family 35, member F2
SMAGP small cell adhesion glycoprotein
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACC2 transforming, acidic coiled-coil containing protein 2
TMEM30B transmembrane protein 30B
TMPO thymopoietin
TOE1 target of EGR1, member 1 (nuclear)
TPBG trophoblast glycoprotein
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBL4A ubiquitin-like 4A
UBXN8 UBX domain protein 8
USP16 ubiquitin specific peptidase 16
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR43 WD repeat domain 43
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF692 zinc finger protein 692
ZZZ3 zinc finger, ZZ-type containing 3