tricarboxylic acid cycle enzyme complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any of the heteromeric enzymes that act in the TCA cycle. (Gene Ontology, GO_0045239)
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Genes

124 proteins co-occuring with the tricarboxylic acid cycle enzyme complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.68947
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 2.38205
MDH1 malate dehydrogenase 1, NAD (soluble) 2.0736
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.03869
ACO2 aconitase 2, mitochondrial 1.99262
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.98337
DLD dihydrolipoamide dehydrogenase 1.95653
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 1.75981
CS citrate synthase 1.62472
FH fumarate hydratase 1.38572
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.15723
PDHX pyruvate dehydrogenase complex, component X 1.11174
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.978559
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.961667
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.905531
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.878251
PFKM phosphofructokinase, muscle 0.859852
TKT transketolase 0.850206
DLAT dihydrolipoamide S-acetyltransferase 0.789191
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.725705
TFEC transcription factor EC 0.708808
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.697344
HK1 hexokinase 1 0.692955
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.676803
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.637578
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.634159
PDK2 pyruvate dehydrogenase kinase, isozyme 2 0.617982
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.617557
GCDH glutaryl-CoA dehydrogenase 0.612895
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.611625
PKLR pyruvate kinase, liver and RBC 0.606128
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.572578
PKM pyruvate kinase, muscle 0.567585
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.557629
SOD2 superoxide dismutase 2, mitochondrial 0.505537
LDHA lactate dehydrogenase A 0.49661
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.490135
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.489327
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 0.45641
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.427891
PIPOX pipecolic acid oxidase 0.421212
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.414164
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 0.40247
SIAE sialic acid acetylesterase 0.399363
GSR glutathione reductase 0.395485
MMD monocyte to macrophage differentiation-associated 0.39471
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.390841
ETFB electron-transfer-flavoprotein, beta polypeptide 0.383509
ASPN asporin 0.37045
AADAT aminoadipate aminotransferase 0.363949
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.355183
ACO1 aconitase 1, soluble 0.348346
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.336619
PC pyruvate carboxylase 0.332472
G6PD glucose-6-phosphate dehydrogenase 0.31783
HADH hydroxyacyl-CoA dehydrogenase 0.304027
TAS1R1 taste receptor, type 1, member 1 0.302168
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.301054
NARS asparaginyl-tRNA synthetase 0.299197
ETF1 eukaryotic translation termination factor 1 0.292527
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.291417
STAP2 signal transducing adaptor family member 2 0.285138
MIPEP mitochondrial intermediate peptidase 0.279612
GLS glutaminase 0.275202
KLK15 kallikrein-related peptidase 15 0.272633
DCTD dCMP deaminase 0.270434
MAOB monoamine oxidase B 0.267871
UMPS uridine monophosphate synthetase 0.267871
OXCT1 3-oxoacid CoA transferase 1 0.265311
CCL15 chemokine (C-C motif) ligand 15 0.256925
GLS2 glutaminase 2 (liver, mitochondrial) 0.256561
MAT2A methionine adenosyltransferase II, alpha 0.237042
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.236324
GLUL glutamate-ammonia ligase 0.235966
INF2 inverted formin, FH2 and WH2 domain containing 0.218563
SIAH2 siah E3 ubiquitin protein ligase 2 0.217861
CRAT carnitine O-acetyltransferase 0.212974
YBX3 Y box binding protein 3 0.212627
MAT1A methionine adenosyltransferase I, alpha 0.183328
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.177724
BRD3 bromodomain containing 3 0.177439
WDFY2 WD repeat and FYVE domain containing 2 0.175745
GPX5 glutathione peroxidase 5 0.173003
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.17141
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.16935
GPX4 glutathione peroxidase 4 0.169099
NADK NAD kinase 0.166167
SUCLG1 succinate-CoA ligase, alpha subunit 0.165231
CAT catalase 0.164089
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.164089
GPX1 glutathione peroxidase 1 0.162546
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.162117
AARS alanyl-tRNA synthetase 0.158012
SNX9 sorting nexin 9 0.157943
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.15776
PGAM2 phosphoglycerate mutase 2 (muscle) 0.156688
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.156342
TPM2 tropomyosin 2 (beta) 0.148741
APOE apolipoprotein E 0.14167
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.140934
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.140734
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.140588
MPV17 MpV17 mitochondrial inner membrane protein 0.139841
DGUOK deoxyguanosine kinase 0.139252
TYMP thymidine phosphorylase 0.138096
C10ORF2 chromosome 10 open reading frame 2 0.138046
GRP gastrin-releasing peptide 0.136863
POLG polymerase (DNA directed), gamma 0.134834
SP100 SP100 nuclear antigen 0.128319
FGF2 fibroblast growth factor 2 (basic) 0.126188
PRODH proline dehydrogenase (oxidase) 1 0.125003
LBR lamin B receptor 0.117753
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.108298
DCX doublecortin 0.10795
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.107772
ELANE elastase, neutrophil expressed 0.106994
BDH1 3-hydroxybutyrate dehydrogenase, type 1 0.106474
LDHAL6A lactate dehydrogenase A-like 6A 0.102031
ACAT1 acetyl-CoA acetyltransferase 1 0.101097
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.100585
PTH parathyroid hormone 0.1004
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.10014
PRSS3 protease, serine, 3 0.100066
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.09969