triamterene-7307 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the triamterene-7307 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM17 ADAM metallopeptidase domain 17
AGGF1 angiogenic factor with G patch and FHA domains 1
AK1 adenylate kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANG angiogenin, ribonuclease, RNase A family, 5
ARMC6 armadillo repeat containing 6
ATAD5 ATPase family, AAA domain containing 5
C16ORF59 chromosome 16 open reading frame 59
CCNA1 cyclin A1
CLCN6 chloride channel, voltage-sensitive 6
CLPS colipase, pancreatic
CPT1A carnitine palmitoyltransferase 1A (liver)
CRY2 cryptochrome circadian clock 2
CUL7 cullin 7
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDN dendrin
DENND2A DENN/MADD domain containing 2A
DTX2 deltex 2, E3 ubiquitin ligase
EFCAB11 EF-hand calcium binding domain 11
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EHBP1L1 EH domain binding protein 1-like 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
FAM63A family with sequence similarity 63, member A
GLB1L galactosidase, beta 1-like
GLRX3 glutaredoxin 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR107 G protein-coupled receptor 107
HDAC11 histone deacetylase 11
HDAC9 histone deacetylase 9
HNF1A HNF1 homeobox A
HOMER3 homer scaffolding protein 3
HOXA4 homeobox A4
IFIH1 interferon induced with helicase C domain 1
IL11 interleukin 11
IVNS1ABP influenza virus NS1A binding protein
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLF4 Kruppel-like factor 4 (gut)
KLHL20 kelch-like family member 20
LINC00260 long intergenic non-protein coding RNA 260
LOC647070 uncharacterized LOC647070
LUC7L LUC7-like (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MAP7 microtubule-associated protein 7
MARS methionyl-tRNA synthetase
MLX MLX, MAX dimerization protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDE1 nudE neurodevelopment protein 1
NEBL nebulette
NFYA nuclear transcription factor Y, alpha
NINJ1 ninjurin 1
NNMT nicotinamide N-methyltransferase
NPM3 nucleophosmin/nucleoplasmin 3
PALM paralemmin
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDGFRL platelet-derived growth factor receptor-like
PEX16 peroxisomal biogenesis factor 16
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQBP1 polyglutamine binding protein 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRR7 proline rich 7 (synaptic)
RALGDS ral guanine nucleotide dissociation stimulator
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REEP2 receptor accessory protein 2
REPS1 RALBP1 associated Eps domain containing 1
SCG5 secretogranin V
SERHL2 serine hydrolase-like 2
SIDT2 SID1 transmembrane family, member 2
SIRT5 sirtuin 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STAC SH3 and cysteine rich domain
STS steroid sulfatase (microsomal), isozyme S
SYT17 synaptotagmin XVII
TCP11 t-complex 11, testis-specific
TESK2 testis-specific kinase 2
TMEM231 transmembrane protein 231
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIM45 tripartite motif containing 45
TTLL7 tubulin tyrosine ligase-like family member 7
UBOX5 U-box domain containing 5
WDR55 WD repeat domain 55
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WWOX WW domain containing oxidoreductase
YIPF2 Yip1 domain family, member 2
ZNF214 zinc finger protein 214
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANOS1 anosmin 1
ANXA10 annexin A10
ARMCX2 armadillo repeat containing, X-linked 2
ATAD2B ATPase family, AAA domain containing 2B
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BANK1 B-cell scaffold protein with ankyrin repeats 1
BEX1 brain expressed, X-linked 1
CAPN5 calpain 5
CBR4 carbonyl reductase 4
CCDC101 coiled-coil domain containing 101
CCNJL cyclin J-like
CCP110 centriolar coiled coil protein 110kDa
CDON cell adhesion associated, oncogene regulated
CENPT centromere protein T
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CST4 cystatin S
CST6 cystatin E/M
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DLK1 delta-like 1 homolog (Drosophila)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGF epidermal growth factor
EIF5A2 eukaryotic translation initiation factor 5A2
EML4 echinoderm microtubule associated protein like 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ESRP2 epithelial splicing regulatory protein 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM53B family with sequence similarity 53, member B
FOXC1 forkhead box C1
FZD3 frizzled class receptor 3
GDAP2 ganglioside induced differentiation associated protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2L G patch domain containing 2-like
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
HLX H2.0-like homeobox
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
IFI30 interferon, gamma-inducible protein 30
INF2 inverted formin, FH2 and WH2 domain containing
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IREB2 iron-responsive element binding protein 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA1549L KIAA1549-like
LMCD1 LIM and cysteine-rich domains 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCMBP minichromosome maintenance complex binding protein
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXRA8 matrix-remodelling associated 8
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NXPH4 neurexophilin 4
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PALMD palmdelphin
PCDHGB5 protocadherin gamma subfamily B, 5
PDZD2 PDZ domain containing 2
PEG3 paternally expressed 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PTCD2 pentatricopeptide repeat domain 2
RAB23 RAB23, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A3 S100 calcium binding protein A3
SCAI suppressor of cancer cell invasion
SDF2 stromal cell-derived factor 2
SERTAD3 SERTA domain containing 3
SIX1 SIX homeobox 1
SLC22A18 solute carrier family 22, member 18
SLITRK5 SLIT and NTRK-like family, member 5
SNHG20 small nucleolar RNA host gene 20
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST5 suppression of tumorigenicity 5
STAR steroidogenic acute regulatory protein
STARD13 StAR-related lipid transfer (START) domain containing 13
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TMEM104 transmembrane protein 104
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPCN1 two pore segment channel 1
TSKU tsukushi, small leucine rich proteoglycan
USP18 ubiquitin specific peptidase 18
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZBTB44 zinc finger and BTB domain containing 44
ZFP69B ZFP69 zinc finger protein B
ZNF107 zinc finger protein 107
ZNF165 zinc finger protein 165
ZNF702P zinc finger protein 702, pseudogene
ZNF711 zinc finger protein 711