tretinoin-966 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tretinoin-966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AJAP1 adherens junctions associated protein 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AOX1 aldehyde oxidase 1
BCL3 B-cell CLL/lymphoma 3
BDKRB2 bradykinin receptor B2
BTG2 BTG family, member 2
C1ORF112 chromosome 1 open reading frame 112
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNO cyclin O
CD22 CD22 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CLMN calmin (calponin-like, transmembrane)
CORO2A coronin, actin binding protein, 2A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSTA cystatin A (stefin A)
CUL3 cullin 3
CYLD cylindromatosis (turban tumor syndrome)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAPK2 death-associated protein kinase 2
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DOPEY2 dopey family member 2
DUSP4 dual specificity phosphatase 4
DVL2 dishevelled segment polarity protein 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPAS1 endothelial PAS domain protein 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FAM174B family with sequence similarity 174, member B
FBLN1 fibulin 1
FZD5 frizzled class receptor 5
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GK3P glycerol kinase 3 pseudogene
GPRC5A G protein-coupled receptor, class C, group 5, member A
HHEX hematopoietically expressed homeobox
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXA5 homeobox A5
HOXB2 homeobox B2
HOXC13 homeobox C13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KAT6B K(lysine) acetyltransferase 6B
KIAA0125 KIAA0125
KIF13B kinesin family member 13B
KLHL24 kelch-like family member 24
KLK6 kallikrein-related peptidase 6
KRT15 keratin 15, type I
LMNA lamin A/C
LRP12 low density lipoprotein receptor-related protein 12
LRP5 low density lipoprotein receptor-related protein 5
MAP1B microtubule-associated protein 1B
MAPK8 mitogen-activated protein kinase 8
NAV2 neuron navigator 2
NPM3 nucleophosmin/nucleoplasmin 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PEX26 peroxisomal biogenesis factor 26
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G10 phospholipase A2, group X
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCD protein kinase C, delta
PRR5 proline rich 5 (renal)
PSG9 pregnancy specific beta-1-glycoprotein 9
PSME4 proteasome (prosome, macropain) activator subunit 4
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RGS16 regulator of G-protein signaling 16
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELL selectin L
SIK1 salt-inducible kinase 1
SIX1 SIX homeobox 1
SKAP2 src kinase associated phosphoprotein 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAGLN transgelin
TENM4 teneurin transmembrane protein 4
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
TMEM209 transmembrane protein 209
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
UBOX5 U-box domain containing 5
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AGO3 argonaute RISC catalytic component 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMOTL2 angiomotin like 2
ANKRD36B ankyrin repeat domain 36B
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BCAR3 breast cancer anti-estrogen resistance 3
BEX4 brain expressed, X-linked 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C11ORF95 chromosome 11 open reading frame 95
C1ORF115 chromosome 1 open reading frame 115
C3ORF52 chromosome 3 open reading frame 52
CALHM2 calcium homeostasis modulator 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTAGE9 CTAGE family, member 9
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DENND5A DENN/MADD domain containing 5A
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUSP8 dual specificity phosphatase 8
EFHC1 EF-hand domain (C-terminal) containing 1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHA2 EPH receptor A2
FA2H fatty acid 2-hydroxylase
FADS3 fatty acid desaturase 3
FICD FIC domain containing
FMO4 flavin containing monooxygenase 4
GHR growth hormone receptor
GNL1 guanine nucleotide binding protein-like 1
GRAMD3 GRAM domain containing 3
HJURP Holliday junction recognition protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGSF3 immunoglobulin superfamily, member 3
INF2 inverted formin, FH2 and WH2 domain containing
IPP intracisternal A particle-promoted polypeptide
IRF3 interferon regulatory factor 3
JAG2 jagged 2
LOC100287590 uncharacterized LOC100287590
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MISP mitotic spindle positioning
MT1H metallothionein 1H
MTMR11 myotubularin related protein 11
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUS81 MUS81 structure-specific endonuclease subunit
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NFE2L3 nuclear factor, erythroid 2-like 3
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PODXL podocalyxin-like
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAD9A RAD9 homolog A (S. pombe)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS17 regulator of G-protein signaling 17
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOB ras homolog family member B
RIC8B RIC8 guanine nucleotide exchange factor B
SERTAD3 SERTA domain containing 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNHG20 small nucleolar RNA host gene 20
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STBD1 starch binding domain 1
SULF1 sulfatase 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THAP1 THAP domain containing, apoptosis associated protein 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM39B transmembrane protein 39B
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC2 trafficking protein particle complex 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
YEATS2 YEATS domain containing 2
ZNF160 zinc finger protein 160
ZNF23 zinc finger protein 23
ZNF248 zinc finger protein 248
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZNF611 zinc finger protein 611
ZNF639 zinc finger protein 639
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN9 zinc finger and SCAN domain containing 9