tranylcypromine-7293 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tranylcypromine-7293 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABHD17B abhydrolase domain containing 17B
AHCYL2 adenosylhomocysteinase-like 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARNT aryl hydrocarbon receptor nuclear translocator
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BMP8A bone morphogenetic protein 8a
C9ORF156 chromosome 9 open reading frame 156
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CBX4 chromobox homolog 4
CCDC40 coiled-coil domain containing 40
CLPS colipase, pancreatic
CPQ carboxypeptidase Q
CSF1R colony stimulating factor 1 receptor
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
EDA ectodysplasin A
FAM110B family with sequence similarity 110, member B
FAM174B family with sequence similarity 174, member B
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCMR Fc fragment of IgM receptor
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11292
GK glycerol kinase
GOLGA2 golgin A2
GTPBP1 GTP binding protein 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA4 homeobox A4
HOXA6 homeobox A6
IFIH1 interferon induced with helicase C domain 1
IL24 interleukin 24
INO80D INO80 complex subunit D
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT6B keratin 6B, type II
LAMA4 laminin, alpha 4
LCT lactase
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LHX1 LIM homeobox 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MGP matrix Gla protein
MOBP myelin-associated oligodendrocyte basic protein
MOCS1 molybdenum cofactor synthesis 1
MTAP methylthioadenosine phosphorylase
MYO1F myosin IF
NF2 neurofibromin 2 (merlin)
NOX1 NADPH oxidase 1
OSBP2 oxysterol binding protein 2
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL2 ovo-like zinc finger 2
PICK1 protein interacting with PRKCA 1
PIP prolactin-induced protein
PPP1R7 protein phosphatase 1, regulatory subunit 7
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PYY peptide YY
RCE1 Ras converting CAAX endopeptidase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS10 regulator of G-protein signaling 10
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SAFB2 scaffold attachment factor B2
SCG5 secretogranin V
SCGB2A2 secretoglobin, family 2A, member 2
SEC24D SEC24 family member D
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SETDB1 SET domain, bifurcated 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOGA1 suppressor of glucose, autophagy associated 1
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT11 synaptotagmin XI
TBC1D22A TBC1 domain family, member 22A
TCP10 t-complex 10
TDRKH tudor and KH domain containing
TESK2 testis-specific kinase 2
TGFB1 transforming growth factor, beta 1
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM231 transmembrane protein 231
TUBA4B tubulin, alpha 4b
TUSC3 tumor suppressor candidate 3
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB7A zinc finger and BTB domain containing 7A
ZNF675 zinc finger protein 675
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ARMC6 armadillo repeat containing 6
ASTE1 asteroid homolog 1 (Drosophila)
BAG4 BCL2-associated athanogene 4
BCAS3 breast carcinoma amplified sequence 3
C1ORF35 chromosome 1 open reading frame 35
CEMIP cell migration inducing protein, hyaluronan binding
CENPT centromere protein T
CEP131 centrosomal protein 131kDa
CFAP44 cilia and flagella associated protein 44
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLASRP CLK4-associating serine/arginine rich protein
CLDN14 claudin 14
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DIXDC1 DIX domain containing 1
DLK1 delta-like 1 homolog (Drosophila)
DRAM1 DNA-damage regulated autophagy modulator 1
DSE dermatan sulfate epimerase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELP3 elongator acetyltransferase complex subunit 3
EPN3 epsin 3
ERF Ets2 repressor factor
EYA4 EYA transcriptional coactivator and phosphatase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM131A family with sequence similarity 131, member A
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GPALPP1 GPALPP motifs containing 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRWD1 glutamate-rich WD repeat containing 1
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
HLX H2.0-like homeobox
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOXC13 homeobox C13
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
IFI6 interferon, alpha-inducible protein 6
IL7R interleukin 7 receptor
IRF2 interferon regulatory factor 2
KIFC1 kinesin family member C1
KIRREL kin of IRRE like (Drosophila)
KISS1 KiSS-1 metastasis-suppressor
KLC2 kinesin light chain 2
KLF11 Kruppel-like factor 11
LPAR6 lysophosphatidic acid receptor 6
MAGOHB mago-nashi homolog B (Drosophila)
MED15 mediator complex subunit 15
MKS1 Meckel syndrome, type 1
MRPL52 mitochondrial ribosomal protein L52
MRPS34 mitochondrial ribosomal protein S34
MTRF1 mitochondrial translational release factor 1
MUM1 melanoma associated antigen (mutated) 1
NCS1 neuronal calcium sensor 1
NRSN2 neurensin 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PALMD palmdelphin
PARD6A par-6 family cell polarity regulator alpha
PDIA3 protein disulfide isomerase family A, member 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX13 peroxisomal biogenesis factor 13
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPCDC phosphopantothenoylcysteine decarboxylase
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB23 RAB23, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RIN1 Ras and Rab interactor 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RPL13P5 ribosomal protein L13 pseudogene 5
S100A3 S100 calcium binding protein A3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STAR steroidogenic acute regulatory protein
TASP1 taspase, threonine aspartase, 1
TPST2 tyrosylprotein sulfotransferase 2
TTC31 tetratricopeptide repeat domain 31
VWA9 von Willebrand factor A domain containing 9
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZMAT5 zinc finger, matrin-type 5
ZNF112 zinc finger protein 112
ZNF324 zinc finger protein 324
ZNF557 zinc finger protein 557
ZNF629 zinc finger protein 629
ZNF816 zinc finger protein 816
ZNHIT2 zinc finger, HIT-type containing 2