tranylcypromine-2264 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tranylcypromine-2264 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACACB acetyl-CoA carboxylase beta
ACBD4 acyl-CoA binding domain containing 4
ACPP acid phosphatase, prostate
ACTA1 actin, alpha 1, skeletal muscle
ADCK2 aarF domain containing kinase 2
AGXT alanine-glyoxylate aminotransferase
AHCYL1 adenosylhomocysteinase-like 1
AKAP13 A kinase (PRKA) anchor protein 13
AKR1D1 aldo-keto reductase family 1, member D1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATF5 activating transcription factor 5
ATP10A ATPase, class V, type 10A
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BTBD18 BTB (POZ) domain containing 18
C9ORF156 chromosome 9 open reading frame 156
CABP2 calcium binding protein 2
CADM4 cell adhesion molecule 4
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC88A coiled-coil domain containing 88A
CD48 CD48 molecule
CD68 CD68 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLEC2D C-type lectin domain family 2, member D
CLGN calmegin
COL16A1 collagen, type XVI, alpha 1
COL9A3 collagen, type IX, alpha 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRH corticotropin releasing hormone
CTSF cathepsin F
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNASE2B deoxyribonuclease II beta
EDN1 endothelin 1
ELL elongation factor RNA polymerase II
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM66D family with sequence similarity 66, member D
FLRT2 fibronectin leucine rich transmembrane protein 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HIST1H3E histone cluster 1, H3e
HOXA6 homeobox A6
HOXB2 homeobox B2
ICAM1 intercellular adhesion molecule 1
IDI2-AS1 IDI2 antisense RNA 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KLF9 Kruppel-like factor 9
KRT15 keratin 15, type I
KRT32 keratin 32, type I
MAPK11 mitogen-activated protein kinase 11
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MLANA melan-A
MMP25 matrix metallopeptidase 25
MSN moesin
MUC6 mucin 6, oligomeric mucus/gel-forming
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OVOL2 ovo-like zinc finger 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX9 paired box 9
PHF7 PHD finger protein 7
PLCB2 phospholipase C, beta 2
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
PPARG peroxisome proliferator-activated receptor gamma
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRDM14 PR domain containing 14
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RGS2 regulator of G-protein signaling 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RTEL1 regulator of telomere elongation helicase 1
SARM1 sterile alpha and TIR motif containing 1
SCN2B sodium channel, voltage gated, type II beta subunit
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SMAD5 SMAD family member 5
SNX13 sorting nexin 13
SOS2 son of sevenless homolog 2 (Drosophila)
SPARCL1 SPARC-like 1 (hevin)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TAS2R1 taste receptor, type 2, member 1
TBCD tubulin folding cofactor D
TBX5 T-box 5
TERT telomerase reverse transcriptase
TLR8 toll-like receptor 8
TM4SF4 transmembrane 4 L six family member 4
TNS1 tensin 1
TP53I11 tumor protein p53 inducible protein 11
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM15 tripartite motif containing 15
ZEB1 zinc finger E-box binding homeobox 1
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BAHCC1 BAH domain and coiled-coil containing 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BHLHE41 basic helix-loop-helix family, member e41
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
C2ORF27A chromosome 2 open reading frame 27A
C4ORF29 chromosome 4 open reading frame 29
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CES3 carboxylesterase 3
CNTN1 contactin 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ETNK2 ethanolamine kinase 2
EXO5 exonuclease 5
F2R coagulation factor II (thrombin) receptor
FBXL7 F-box and leucine-rich repeat protein 7
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR27 G protein-coupled receptor 27
GRPR gastrin-releasing peptide receptor
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
INO80D INO80 complex subunit D
IQCG IQ motif containing G
KIAA0319L KIAA0319-like
KLHL28 kelch-like family member 28
KRT24 keratin 24, type I
LAMB3 laminin, beta 3
LAX1 lymphocyte transmembrane adaptor 1
LIF leukemia inhibitory factor
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC390998 ribosomal protein L10 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NIPAL2 NIPA-like domain containing 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OSMR oncostatin M receptor
PC pyruvate carboxylase
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITX2 paired-like homeodomain 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRKD3 protein kinase D3
RAB3A RAB3A, member RAS oncogene family
RCAN3 RCAN family member 3
RIN2 Ras and Rab interactor 2
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
STARD3 StAR-related lipid transfer (START) domain containing 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM180 transmembrane protein 180
TPCN1 two pore segment channel 1
TPST2 tyrosylprotein sulfotransferase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WLS wntless Wnt ligand secretion mediator
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZBTB33 zinc finger and BTB domain containing 33
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF211 zinc finger protein 211
ZNF574 zinc finger protein 574
ZNF580 zinc finger protein 580
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76